Metabolic Complications among Korean Patients with HIV Infection: The Korea HIV/AIDS Cohort Study
DC Field | Value | Language |
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dc.contributor.author | Oh, Dong Hyun | - |
dc.contributor.author | Ahn, Jin Young | - |
dc.contributor.author | Kim, Sang Il | - |
dc.contributor.author | Kim, Min Ja | - |
dc.contributor.author | Woo, Jun Hee | - |
dc.contributor.author | Kim, Woo Joo | - |
dc.contributor.author | Baek, Ji Hyeon | - |
dc.contributor.author | Kim, Shin-Woo | - |
dc.contributor.author | Choi, Bo Youl | - |
dc.contributor.author | Lee, Mi Hwa | - |
dc.contributor.author | Choi, Ju-Yeon | - |
dc.contributor.author | Han, Myung Guk | - |
dc.contributor.author | Kang, Chun | - |
dc.contributor.author | Kim, June Myung | - |
dc.contributor.author | Choi, Jun Yong | - |
dc.date.accessioned | 2021-09-03T03:38:41Z | - |
dc.date.available | 2021-09-03T03:38:41Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2017-08 | - |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/82749 | - |
dc.description.abstract | Currently, metabolic complications are the most common problem among human immunodeficiency virus (HIV)-infected patients, with a high incidence. However, there have been very few studies regarding metabolic abnormalities published in Asia, especially in Korea. This cross-sectional study was performed to investigate the prevalence of and risk factors for metabolic abnormalities in 1,096 HIV-infected patients of the Korea HIV/AIDS cohort study enrolled from 19 hospitals between 2006 and 2013. Data at entry to cohort were analyzed. As a result, the median age of the 1,096 enrolled subjects was 46 years, and most patients were men (92.8%). The metabolic profiles of the patients were as follows: median weight was 63.8 kg, median body mass index (BMI) was 22.2 kg/m(2), and 16.4% of the patients had a BMI over 25 kg/m(2). A total of 5.5% of the patients had abdominal obesity (waist/hip ratio >= 1 in men, >= 0.85 in women). Increased levels of fasting glucose, total cholesterol, low-density lipoprotein (LDL) cholesterol, and triglycerides were present in 10.4%, 6.0%, 5.5%, and 32.1% of the patients. Decreased high-density lipoprotein (HDL) cholesterol levels were observed in 44.2% of the patients. High systolic blood pressure was present in 14.3% of the patients. In multivariate analysis, high BMI and the use of protease inhibitors (PIs) were risk factors for dyslipidemia in HIV-infected patients. In conclusion, proper diagnosis and management should be offered for the prevalent metabolic complications of Korean HIV-infected patients. Further studies on risk factors for metabolic complications are needed. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KOREAN ACAD MEDICAL SCIENCES | - |
dc.subject | ACTIVE ANTIRETROVIRAL THERAPY | - |
dc.subject | BODY-COMPOSITION CHANGES | - |
dc.subject | INSULIN-RESISTANCE | - |
dc.subject | PREVALENCE | - |
dc.subject | RISK | - |
dc.subject | ASSOCIATIONS | - |
dc.subject | DISEASE | - |
dc.subject | CARE | - |
dc.title | Metabolic Complications among Korean Patients with HIV Infection: The Korea HIV/AIDS Cohort Study | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Min Ja | - |
dc.contributor.affiliatedAuthor | Kim, Woo Joo | - |
dc.identifier.doi | 10.3346/jkms.2017.32.8.1268 | - |
dc.identifier.scopusid | 2-s2.0-85021718261 | - |
dc.identifier.wosid | 000405169100010 | - |
dc.identifier.bibliographicCitation | JOURNAL OF KOREAN MEDICAL SCIENCE, v.32, no.8, pp.1268 - 1274 | - |
dc.relation.isPartOf | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.citation.title | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.citation.volume | 32 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 1268 | - |
dc.citation.endPage | 1274 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | ACTIVE ANTIRETROVIRAL THERAPY | - |
dc.subject.keywordPlus | BODY-COMPOSITION CHANGES | - |
dc.subject.keywordPlus | INSULIN-RESISTANCE | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | ASSOCIATIONS | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordPlus | CARE | - |
dc.subject.keywordAuthor | HIV Infection | - |
dc.subject.keywordAuthor | Metabolic Complication | - |
dc.subject.keywordAuthor | Dyslipidemia | - |
dc.subject.keywordAuthor | Protease Inhibitor | - |
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