Diagnostic accuracy of anti-Sa and anti-RA33 antibodies in rheumatoid arthritis: a meta-analysis
DC Field | Value | Language |
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dc.contributor.author | Lee, Y. H. | - |
dc.contributor.author | Bae, S. C. | - |
dc.date.accessioned | 2021-09-03T03:43:38Z | - |
dc.date.available | 2021-09-03T03:43:38Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2017-08 | - |
dc.identifier.issn | 0340-1855 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/82776 | - |
dc.description.abstract | Objective. This study evaluated the diagnostic accuracy of anti-Sa and anti-RA33 antibodies in rheumatoid arthritis (RA). Methods. PubMed, Embase, and Cochrane library databases were searched for relevant studies, and 2 meta-analyseswere performed to determine the diagnostic accuracy of anti-Sa and anti-RA33 antibodies in patients with RA. Results. The meta-analysis included 17 studies. Pooled sensitivity and specificity of anti-Sa antibody were 39.5% (95% confidence interval [CI] 36.5-42.4) and 96.8% (95 % CI 95.9-97.4), respectively, and those of anti-RA33 antibody were 31.8% (95 % CI 28.7-35.0) and 90.1% (95 % CI 87.8-92.1), respectively. PLR, NLR, and DOR of anti-Sa antibody were 14.11 (95% CI 7.076-28.13), 0.607 (95% CI 0.558-0.703), and 22.76 (95% C, 11.10-46.69), respectively, and those of anti-RA33 antibody were 3.429 (95% CI 2.039-5.765), 0.761 (95% CI 0.681-0.851), and 4.597 (95 % CI 2.602-8.121), respectively. AUC and Q* index for anti-Sa antibody were 0.558 and 0.543, respectively, while those for anti-RA33 antibody were 0.501 and 0.500, respectively. Conclusions. Our meta-analysis indicated that both anti-Sa and anti-RA33 antibodies were highly specific but not sensitive for diagnosing RA. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | SPRINGER HEIDELBERG | - |
dc.subject | CYCLIC CITRULLINATED PEPTIDE | - |
dc.subject | CONNECTIVE-TISSUE DISEASE | - |
dc.subject | ANTINUCLEAR ANTIBODY | - |
dc.subject | AUTOANTIBODIES | - |
dc.subject | ANTIKERATIN | - |
dc.title | Diagnostic accuracy of anti-Sa and anti-RA33 antibodies in rheumatoid arthritis: a meta-analysis | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Y. H. | - |
dc.identifier.doi | 10.1007/s00393-016-0134-y | - |
dc.identifier.scopusid | 2-s2.0-84975131336 | - |
dc.identifier.wosid | 000407505900013 | - |
dc.identifier.bibliographicCitation | ZEITSCHRIFT FUR RHEUMATOLOGIE, v.76, no.6, pp.535 - 538 | - |
dc.relation.isPartOf | ZEITSCHRIFT FUR RHEUMATOLOGIE | - |
dc.citation.title | ZEITSCHRIFT FUR RHEUMATOLOGIE | - |
dc.citation.volume | 76 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 535 | - |
dc.citation.endPage | 538 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Rheumatology | - |
dc.relation.journalWebOfScienceCategory | Rheumatology | - |
dc.subject.keywordPlus | CYCLIC CITRULLINATED PEPTIDE | - |
dc.subject.keywordPlus | CONNECTIVE-TISSUE DISEASE | - |
dc.subject.keywordPlus | ANTINUCLEAR ANTIBODY | - |
dc.subject.keywordPlus | AUTOANTIBODIES | - |
dc.subject.keywordPlus | ANTIKERATIN | - |
dc.subject.keywordAuthor | Rheumatoid arthritis | - |
dc.subject.keywordAuthor | Anti-Sa antibody | - |
dc.subject.keywordAuthor | Anti-RA33 antibody | - |
dc.subject.keywordAuthor | Diagnostic accuracy | - |
dc.subject.keywordAuthor | Connective tissue diseases | - |
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