Interaction of obstructive sleep apnoea and cognitive impairment with slow gait speed in middle-aged and older adults
- Authors
- Lee, Sunghee; Shin, Chol
- Issue Date
- 7월-2017
- Publisher
- OXFORD UNIV PRESS
- Keywords
- gait; cognition; obstructive sleep apnoea; older people
- Citation
- AGE AND AGEING, v.46, no.4, pp.653 - 659
- Indexed
- SCIE
SCOPUS
- Journal Title
- AGE AND AGEING
- Volume
- 46
- Number
- 4
- Start Page
- 653
- End Page
- 659
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/82877
- DOI
- 10.1093/ageing/afw228
- ISSN
- 0002-0729
- Abstract
- to investigate whether slow gait speed is associated with cognitive impairment and further whether the association is modified by obstructive sleep apnoea (OSA). in total, 2,222 adults aged 49-80 years, free from dementia, stroke and head injury were asked to walk a 4-m course at fast and usual gait speeds. The time taken to walk was measured. All participants completed the Korean Mini-Mental State Examination, which was validated in the Korean language, to assess cognitive function. Additionally, the participants completed a polysomnography test to ascertain OSA (defined as an apnoea-hypopnoea index 15). Multivariable linear regression models were utilised to test the associations. time taken to walk 4 m showed significant inverse associations with cognitive scores (P value = 0.001 at fast gait speed and P = 0.002 at usual gait speed). Furthermore, a significant interaction according to OSA on the association between time to walk and cognitive impairment was found (P value for interaction = 0.003 at fast gait speed and P value for interaction = 0.007 at usual gait speed). we found that the inverse association between the time taken to walk 4 m and a cognitive score became significantly stronger, if an individual had OSA.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.