Efficacy and Safety of Tranexamic Acid in Melasma: A Meta-analysis and Systematic Review
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Hyun Jung | - |
dc.contributor.author | Moon, Seok Hoon | - |
dc.contributor.author | Cho, Sang Hyun | - |
dc.contributor.author | Lee, Jeong Deuk | - |
dc.contributor.author | Kim, Hei Sung | - |
dc.date.accessioned | 2021-09-03T04:29:50Z | - |
dc.date.available | 2021-09-03T04:29:50Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2017-07 | - |
dc.identifier.issn | 0001-5555 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/82970 | - |
dc.description.abstract | Tranexamic acid is a novel treatment option for melasma; however, there is no consensus on its use. This systematic review searched major databases for relevant publications to March 2016. Eleven studies with 667 participants were included. Pooled data from tranexamic acid-only observational studies with pre- and post-treatment Melasma Area and Severity Index (MASI) showed a decrease of 1.60 in MASI (95% confidence interval (CI), 1.20-2.00; p < 0.001) after treatment with tranexamic acid. The addition of tranexamic acid to routine treatment modalities resulted in a further decrease in MASI of 0.94 (95% CI 0.10-1.79; p = 0.03). Side-effects were minor, with a few cases reporting hypo-menorrhoea, mild abdominal discomfort, and transient skin irritation. These results support the efficacy and safety of tranexamic acid, either alone or as an adjuvant to routine treatment modalities for melasma. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ACTA DERMATO-VENEREOLOGICA | - |
dc.subject | TRIPLE-COMBINATION CREAM | - |
dc.subject | LASER | - |
dc.title | Efficacy and Safety of Tranexamic Acid in Melasma: A Meta-analysis and Systematic Review | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Hyun Jung | - |
dc.identifier.doi | 10.2340/00015555-2668 | - |
dc.identifier.scopusid | 2-s2.0-85021894624 | - |
dc.identifier.wosid | 000405580200002 | - |
dc.identifier.bibliographicCitation | ACTA DERMATO-VENEREOLOGICA, v.97, no.7, pp.776 - 781 | - |
dc.relation.isPartOf | ACTA DERMATO-VENEREOLOGICA | - |
dc.citation.title | ACTA DERMATO-VENEREOLOGICA | - |
dc.citation.volume | 97 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 776 | - |
dc.citation.endPage | 781 | - |
dc.type.rims | ART | - |
dc.type.docType | Review | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Dermatology | - |
dc.relation.journalWebOfScienceCategory | Dermatology | - |
dc.subject.keywordPlus | TRIPLE-COMBINATION CREAM | - |
dc.subject.keywordPlus | LASER | - |
dc.subject.keywordAuthor | tranexamic acid | - |
dc.subject.keywordAuthor | melasma: systematic review | - |
dc.subject.keywordAuthor | meta-analysis | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.