Idiopathic inflammatory myopathy and the risk of venous thromboembolism: a meta-analysis
- Authors
- Lee, Young Ho; Song, Gwan Gyu
- Issue Date
- 7월-2017
- Publisher
- SPRINGER HEIDELBERG
- Keywords
- Polymyositis; Dermatomyositis; Venous thromboembolism
- Citation
- RHEUMATOLOGY INTERNATIONAL, v.37, no.7, pp.1165 - 1173
- Indexed
- SCIE
SCOPUS
- Journal Title
- RHEUMATOLOGY INTERNATIONAL
- Volume
- 37
- Number
- 7
- Start Page
- 1165
- End Page
- 1173
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/82990
- DOI
- 10.1007/s00296-017-3735-0
- ISSN
- 0172-8172
- Abstract
- This study aimed at analyzing published data on the association between idiopathic inflammatory myopathy and venous thromboembolism (VTE). We examined studies on VTE risk in patients with polymyositis (PM) and/or dermatomyositis (DM), in the MEDLINE, EMBASE, and Cochrane databases and via manual searches. We performed a meta-analysis on the relative risks (RRs) of VTE, pulmonary embolism (PE), and deep vein thrombosis (DVT) in these patients. Five studies, including 8858 patients with PM/DM met the inclusion criteria. Meta-analysis revealed a significant association between PM/DM and VTE risk (RR = 4.364, 95% CI 2.128-8.949, p = 5.8 x 10(-5)). A significant association was found between PE risk and PM/DM (RR = 3.504, 95% CI 2.856-4.300, p < 1.0 x 10(-8)). Meta-analysis also indicated a significant association between DVT risk and PM/DM (RR = 7.481, 95% CI 3.355-16.68, p = 8.7 x 10(-7)). This meta-analysis demonstrated that both types of PM/DM are associated with an elevated risk of VTE, PE, and DVT, suggesting that patients with PM/DM should be carefully monitored for development of these conditions.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.