Effect of Changes in Body Mass Index on Cardiovascular Outcomes in Kidney Transplant Recipients
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, K. Y. | - |
dc.contributor.author | Cho, J. -H. | - |
dc.contributor.author | Jung, H. -Y. | - |
dc.contributor.author | Choi, J. -Y. | - |
dc.contributor.author | Park, S. -H. | - |
dc.contributor.author | Kim, C. -D. | - |
dc.contributor.author | Kim, Y. -L. | - |
dc.contributor.author | Ro, H. | - |
dc.contributor.author | Lee, S. | - |
dc.contributor.author | Han, S. -Y. | - |
dc.contributor.author | Jung, C. W. | - |
dc.contributor.author | Park, J. B. | - |
dc.contributor.author | Kim, M. S. | - |
dc.contributor.author | Yang, J. | - |
dc.contributor.author | Ahn, C. | - |
dc.date.accessioned | 2021-09-03T05:16:52Z | - |
dc.date.available | 2021-09-03T05:16:52Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2017-06 | - |
dc.identifier.issn | 0041-1345 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/83199 | - |
dc.description.abstract | Background. A higher body mass index (BMI) before kidney transplantation (KT) is associated with increased mortality and allograft loss in kidney transplant recipients (KTRs). However, the effect of changes in BMI after KT on these outcomes remains uncertain. The aim of this study was to investigate the effect of baseline BMI and changes in BMI on clinical outcomes in KTRs. Methods. A total of 869 KTRs were enrolled from a multicenter observational cohort study from 2012 to 2015. Patients were divided into low and high BMI groups before KT based on a BMI cutoff point of 23 kg/m(2). Differences in acute rejection and cardiovascular disease (CVD) between the 2 groups were analyzed. In addition, clinical outcomes across the 4 BMI groups divided by BMI change 1 year after KT were compared. Associations between BMI change and laboratory findings were also evaluated. Results. Patients with a higher BMI before KT showed significantly increased CVD after KT (P = .027) compared with patients with a lower BMI. However, among the KTRs with a higher baseline BMI, only persistently higher BMI was associated with increased CVD during the follow-up period (P = .003). Patients with persistently higher BMI had significantly decreased high-density lipoprotein cholesterol and increased hemoglobin, triglyceride, and hemoglobin A1c levels. Baseline BMI and post-transplantation change in BMI were not related to acute rejection in KTRs. Conclusions. BMI in the 1st year after KT as well as baseline BMI were associated with CVD in KTRs. More careful monitoring of obese KTRs who do not undergo a reduction in BMI after KT is required. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.subject | RENAL-TRANSPLANTATION | - |
dc.subject | ASSOCIATION | - |
dc.subject | MORTALITY | - |
dc.subject | REALITY | - |
dc.subject | OBESITY | - |
dc.subject | DISEASE | - |
dc.subject | RISK | - |
dc.title | Effect of Changes in Body Mass Index on Cardiovascular Outcomes in Kidney Transplant Recipients | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Jung, C. W. | - |
dc.identifier.doi | 10.1016/j.transproceed.2017.03.049 | - |
dc.identifier.scopusid | 2-s2.0-85020130269 | - |
dc.identifier.wosid | 000403382400025 | - |
dc.identifier.bibliographicCitation | TRANSPLANTATION PROCEEDINGS, v.49, no.5, pp.1038 - 1042 | - |
dc.relation.isPartOf | TRANSPLANTATION PROCEEDINGS | - |
dc.citation.title | TRANSPLANTATION PROCEEDINGS | - |
dc.citation.volume | 49 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 1038 | - |
dc.citation.endPage | 1042 | - |
dc.type.rims | ART | - |
dc.type.docType | Article; Proceedings Paper | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Immunology | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalResearchArea | Transplantation | - |
dc.relation.journalWebOfScienceCategory | Immunology | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.relation.journalWebOfScienceCategory | Transplantation | - |
dc.subject.keywordPlus | RENAL-TRANSPLANTATION | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordPlus | REALITY | - |
dc.subject.keywordPlus | OBESITY | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordPlus | RISK | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.