Predicting Extrathyroidal Extension in Patients With Papillary Thyroid Microcarcinoma According to a BRAF Mutation
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Doh Young | - |
dc.contributor.author | Hwang, Soo Min | - |
dc.contributor.author | An, Jee Hyun | - |
dc.contributor.author | Son, Kyu Ri | - |
dc.contributor.author | Baek, Seung-Kuk | - |
dc.contributor.author | Kim, Sin Gon | - |
dc.contributor.author | Chae, Yang Seok | - |
dc.contributor.author | Jung, Kwang-Yoon | - |
dc.date.accessioned | 2021-09-03T05:56:21Z | - |
dc.date.available | 2021-09-03T05:56:21Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2017-06 | - |
dc.identifier.issn | 1976-8710 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/83404 | - |
dc.description.abstract | Objectives. The aim of this study was to evaluate the association between preoperative parameters and extrathyroidal extension (ETE) of papillary thyroid microcarcinoma (PTMC) according to the BRAF mutation and to evaluate the preoperative predictability of ETE. Methods. We analyzed the medical records of 332 patients with PTMC (140 in the BRAF group and 192 in the BRAF+group). The presence of ETE was subjected to a correlation analysis with age, sex, tumor size, clinical nodal status, and ultrasonography (US) findings. Among the US findings, the correlation between tumors and the thyroid capsule was, categorized into four groups; US group A, intraparechymal; US group B, tumor abutting the capsule <50% of diameter; US group C, tumor abutting >50% of diameter; and US group D, tumor destroyed the capsule. The predictive value of ETE, including sensitivity, specificity, and positive and negative predictive values were evaluated. Results. Tumor size and US group were significantly correlated with gross ELL in the BRAF and BRAF+ groups. Tumor size of 0.5 cm and US groups B and C in the BRAF group were cutoff values for gross ETE;, with a negative predictive value of 100%, whereas tumor size of 0.7 cm and US groups A and B in the BRAF+ group had negative predictive values of 92.4% and 100%, respectively. Conclusion. Excluding of ETE by US was categorized according to tumor size and US findings. A different categorization to exclude ETE is needed according to the BRAF mutation. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SOC OTORHINOLARYNGOL | - |
dc.subject | V600E MUTATION | - |
dc.subject | BRAF(V600E) MUTATION | - |
dc.subject | CARCINOMA | - |
dc.subject | CANCER | - |
dc.subject | ASSOCIATION | - |
dc.subject | ULTRASOUND | - |
dc.subject | LOBECTOMY | - |
dc.subject | IMPACT | - |
dc.title | Predicting Extrathyroidal Extension in Patients With Papillary Thyroid Microcarcinoma According to a BRAF Mutation | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Chae, Yang Seok | - |
dc.contributor.affiliatedAuthor | Jung, Kwang-Yoon | - |
dc.identifier.doi | 10.21053/ceo.2015.01655 | - |
dc.identifier.scopusid | 2-s2.0-85018680037 | - |
dc.identifier.wosid | 000402589900009 | - |
dc.identifier.bibliographicCitation | CLINICAL AND EXPERIMENTAL OTORHINOLARYNGOLOGY, v.10, no.2, pp.174 - 180 | - |
dc.relation.isPartOf | CLINICAL AND EXPERIMENTAL OTORHINOLARYNGOLOGY | - |
dc.citation.title | CLINICAL AND EXPERIMENTAL OTORHINOLARYNGOLOGY | - |
dc.citation.volume | 10 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 174 | - |
dc.citation.endPage | 180 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002231998 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Otorhinolaryngology | - |
dc.relation.journalWebOfScienceCategory | Otorhinolaryngology | - |
dc.subject.keywordPlus | V600E MUTATION | - |
dc.subject.keywordPlus | BRAF(V600E) MUTATION | - |
dc.subject.keywordPlus | CARCINOMA | - |
dc.subject.keywordPlus | CANCER | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.subject.keywordPlus | ULTRASOUND | - |
dc.subject.keywordPlus | LOBECTOMY | - |
dc.subject.keywordPlus | IMPACT | - |
dc.subject.keywordAuthor | Papillary Thyroid Microcarcinoma | - |
dc.subject.keywordAuthor | BRAF Mutation | - |
dc.subject.keywordAuthor | Extrathyroidal Extension | - |
dc.subject.keywordAuthor | Capsules | - |
dc.subject.keywordAuthor | Size | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
145 Anam-ro, Seongbuk-gu, Seoul, 02841, Korea+82-2-3290-2963
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.