Delay of insulin initiation in patients with type 2 diabetes mellitus inadequately controlled with oral hypoglycemic agents (analysis of patient- and physician-related factors): A prospective observational DIPP-FACTOR study in Korea
DC Field | Value | Language |
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dc.contributor.author | Kim, Sin Gon | - |
dc.contributor.author | Kim, Nam Hoon | - |
dc.contributor.author | Ku, Bon Jeong | - |
dc.contributor.author | Shon, Ho Sang | - |
dc.contributor.author | Kim, Doo Man | - |
dc.contributor.author | Park, Tae Sun | - |
dc.contributor.author | Kim, Yong-Seong | - |
dc.contributor.author | Kim, In Joo | - |
dc.contributor.author | Choi, Dong Seop | - |
dc.date.accessioned | 2021-09-03T06:34:56Z | - |
dc.date.available | 2021-09-03T06:34:56Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2017-05 | - |
dc.identifier.issn | 2040-1116 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/83552 | - |
dc.description.abstract | Aims/Introduction: To assess the time to initiation of insulin therapy, and concurrently investigate both patient- and physician-related factors associated with delaying insulin therapy in Korean patients with type 2 diabetes uncontrolled by oral hypoglycemic agents (OHAs). Materials and Methods: This prospective, observational disease registry study was carried out across 69 centers in Korea. Type 2 diabetes patients who had received two or more OHAs within the past 5 years, had a glycated hemoglobin 8% in the past 6 months and had not received insulin were included. Data recorded on data collection forms during a 12-month period were analyzed. Results: Of 2168 patients enrolled, 1959 were evaluated and classified as the insulin-initiated or insulin-delayed group. Insulin was prescribed for just 20% of the patients during a 1-year follow-up period, and less than half (44.5%) of the patients who were taking two OHAs started insulin after 6 years. Patient-related factors for delay in insulin initiation included older age, shorter duration of diabetes and lower glycated hemoglobin. Physician-related factors included age (similar to 50 to <60 years), sex (women) and number (<1000) of patients consulted per month. Patient refusal (33.6%) and physicians' concerns of patient non-compliance (26.5%) were the major physician-reported reasons for delaying insulin therapy. Inconvenience of insulin therapy (51.6%) and fear of injection (48.2%) were the major reasons for patient refusal. Conclusions: Insulin initiation is delayed in patients with type 2 diabetes uncontrolled by two or more OHAs in Korea. Patient- and physician-related factors associated with this delay need to be addressed for better diabetes management. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | WILEY | - |
dc.subject | GLYCEMIC CONTROL | - |
dc.subject | THERAPY | - |
dc.subject | MANAGEMENT | - |
dc.subject | FAILURE | - |
dc.subject | HYPERGLYCEMIA | - |
dc.subject | METFORMIN | - |
dc.subject | UK | - |
dc.title | Delay of insulin initiation in patients with type 2 diabetes mellitus inadequately controlled with oral hypoglycemic agents (analysis of patient- and physician-related factors): A prospective observational DIPP-FACTOR study in Korea | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Sin Gon | - |
dc.contributor.affiliatedAuthor | Kim, Nam Hoon | - |
dc.identifier.doi | 10.1111/jdi.12581 | - |
dc.identifier.scopusid | 2-s2.0-85017361545 | - |
dc.identifier.wosid | 000400971000012 | - |
dc.identifier.bibliographicCitation | JOURNAL OF DIABETES INVESTIGATION, v.8, no.3, pp.346 - 353 | - |
dc.relation.isPartOf | JOURNAL OF DIABETES INVESTIGATION | - |
dc.citation.title | JOURNAL OF DIABETES INVESTIGATION | - |
dc.citation.volume | 8 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 346 | - |
dc.citation.endPage | 353 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Endocrinology & Metabolism | - |
dc.relation.journalWebOfScienceCategory | Endocrinology & Metabolism | - |
dc.subject.keywordPlus | GLYCEMIC CONTROL | - |
dc.subject.keywordPlus | THERAPY | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | FAILURE | - |
dc.subject.keywordPlus | HYPERGLYCEMIA | - |
dc.subject.keywordPlus | METFORMIN | - |
dc.subject.keywordPlus | UK | - |
dc.subject.keywordAuthor | Insulin therapy | - |
dc.subject.keywordAuthor | Physician and patient behaviors | - |
dc.subject.keywordAuthor | Type 2 diabetes | - |
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