Between-visit reproducibility of inter-arm systolic blood pressure differences in treated hypertensive patients: the coconet study
- Authors
- Kim, Jang Young; Kim, Eung Ju; Namgung, June; Cho, Byung-Ryul; Nam, Chang-Wook; Kim, Young-Kwon; Park, Jeong Bae
- Issue Date
- 5월-2017
- Publisher
- NATURE PUBLISHING GROUP
- Keywords
- Follow-up; Inter-arm blood pressure; Reproducibility; Risk factor
- Citation
- HYPERTENSION RESEARCH, v.40, no.5, pp.483 - 486
- Indexed
- SCIE
SCOPUS
- Journal Title
- HYPERTENSION RESEARCH
- Volume
- 40
- Number
- 5
- Start Page
- 483
- End Page
- 486
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/83689
- DOI
- 10.1038/hr.2016.173
- ISSN
- 0916-9636
- Abstract
- Inter-arm systolic blood pressure (BP) differences (sIADs) have recently been recognized as a risk factor for cardiovascular mortality. However, sIAD reproducibility remains unresolved from a controlled trial perspective. We evaluated the between-visit reproducibility of sIADs in hypertensive patients. We examined 1875 hypertensive participants aged 20 years and older (mean age: 62.3 years, 45.4% female) from nine primary clinics and 27 secondary and tertiary hospitals. The BPs in both arms were automatically and simultaneously measured in triplicate with a cuff-oscillometric BP device. BP measurements were obtained at baseline and at 3-month follow-up time points. Increased sIAD was defined as an absolute difference of >= 10 mm Hg in the average systolic BPs between the left and right arms. The overall mean sIAD was 4.33 +/- 4.17 mm Hg. The prevalences of increased sIAD at baseline and at the 3-month measurements were 7.6% and 7.1%, respectively. The intraclass correlation coefficient for the between-visit sIADs was 0.304 (95% confidence interval (CI) 0.262-0.344). The kappa-value between the baseline and follow-up increased sIADs was 0.165 (95% CI 0.096-0.234). The percentage of patients who exhibited an increased sIAD at 3 months compared with the initially increased sIAD at baseline was 21.8%. The reproducibility of sIAD determination between baseline and the 3-month follow-up measurements lacked agreement in the hypertensive patients. Further studies should identify the relevant variables and characteristics of this poor reproducibility (CRIS number; KCT0001235).
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