Value of Serum Cystatin C Measurement in the Diagnosis of Sepsis-Induced Kidney Injury and Prediction of Renal Function Recovery
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Leem, Ah Young | - |
dc.contributor.author | Park, Moo Suk | - |
dc.contributor.author | Park, Byung Hoon | - |
dc.contributor.author | Jung, Won Jai | - |
dc.contributor.author | Chung, Kyung Soo | - |
dc.contributor.author | Kim, Song Yee | - |
dc.contributor.author | Kim, Eun Young | - |
dc.contributor.author | Jung, Ji Ye | - |
dc.contributor.author | Kang, Young Ae | - |
dc.contributor.author | Kim, Young Sam | - |
dc.contributor.author | Kim, Se Kyu | - |
dc.contributor.author | Chang, Joon | - |
dc.contributor.author | Song, Joo Han | - |
dc.date.accessioned | 2021-09-03T07:01:04Z | - |
dc.date.available | 2021-09-03T07:01:04Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2017-05 | - |
dc.identifier.issn | 0513-5796 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/83702 | - |
dc.description.abstract | Purpose: Acute kidney injury (AKI) is common in critically ill patients. Serum cystatin C has emerged as a reliable marker of AKI. We sought to assess the value of serum cystatin C for early detection and prediction of renal function recovery in patients with sepsis. Materials and Methods: Sepsis patients (113 AKI patients and 49 non-AKI patients) admitted to the intensive care unit (ICU) were included. Serum creatinine and cystatin C levels and glomerular filtration rate were measured on days 0, 1, 3, and 7. Results: Serum cystatin C levels were significantly higher in AKI patients than in non-AKI patients at all time points. Multivariate analysis showed that only serum cystatin C levels on day 0 were associated with AKI development [odds ratio (OR)=19.30; 95% confidence interval (CI)=2.58-144.50, p< 0.001]. Linear mixed model analysis showed significant variation in cystatin C levels between the recovery and non-recovery groups over time (p=0.001). High levels of serum cystatin C at day 0 (OR=1.64; 95% CI=1.00-2.68, p=0.048) were associated with recovery of AKI. Conclusion: Serum cystatin C level was found to be associated with the development and worsening of AKI in ICU patients with sepsis. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | YONSEI UNIV COLL MEDICINE | - |
dc.subject | GELATINASE-ASSOCIATED LIPOCALIN | - |
dc.subject | CRITICALLY-ILL PATIENTS | - |
dc.subject | GLOMERULAR-FILTRATION-RATE | - |
dc.subject | FAILURE | - |
dc.subject | CREATININE | - |
dc.subject | THERAPY | - |
dc.subject | MANAGEMENT | - |
dc.subject | MARKERS | - |
dc.subject | PLASMA | - |
dc.subject | IMPACT | - |
dc.title | Value of Serum Cystatin C Measurement in the Diagnosis of Sepsis-Induced Kidney Injury and Prediction of Renal Function Recovery | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Jung, Won Jai | - |
dc.identifier.doi | 10.3349/ymj.2017.58.3.604 | - |
dc.identifier.scopusid | 2-s2.0-85016209050 | - |
dc.identifier.wosid | 000404601400018 | - |
dc.identifier.bibliographicCitation | YONSEI MEDICAL JOURNAL, v.58, no.3, pp.604 - 612 | - |
dc.relation.isPartOf | YONSEI MEDICAL JOURNAL | - |
dc.citation.title | YONSEI MEDICAL JOURNAL | - |
dc.citation.volume | 58 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 604 | - |
dc.citation.endPage | 612 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002216176 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | GELATINASE-ASSOCIATED LIPOCALIN | - |
dc.subject.keywordPlus | CRITICALLY-ILL PATIENTS | - |
dc.subject.keywordPlus | GLOMERULAR-FILTRATION-RATE | - |
dc.subject.keywordPlus | FAILURE | - |
dc.subject.keywordPlus | CREATININE | - |
dc.subject.keywordPlus | THERAPY | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | MARKERS | - |
dc.subject.keywordPlus | PLASMA | - |
dc.subject.keywordPlus | IMPACT | - |
dc.subject.keywordAuthor | Sepsis | - |
dc.subject.keywordAuthor | acute kidney injury | - |
dc.subject.keywordAuthor | cystatin C | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.