Approach to cytomegalovirus infections in patients with ulcerative colitis
DC Field | Value | Language |
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dc.contributor.author | Park, Sung Chul | - |
dc.contributor.author | Jeen, Yoon Mi | - |
dc.contributor.author | Jeen, Yoon Tae | - |
dc.date.accessioned | 2021-09-03T07:02:13Z | - |
dc.date.available | 2021-09-03T07:02:13Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2017-05 | - |
dc.identifier.issn | 1226-3303 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/83708 | - |
dc.description.abstract | Cytomegalovirus (CMV) reactivation is common in patients with severe ulcerative colitis (UC), and may reflect exacerbation of mucosal inflammation and/or administration of immunosuppressants. The question of whether CMV is an active pathogen or 'an innocent bystander' in the exacerbation of UC remains controversial. Patients with UC exacerbated by reactivated CMV experience worse prognoses than those without CMV reactivation and antiviral therapy significantly reduces the need for colectomy in patients with severe UC and high-grade CMV infection, indicating that CMV plays a role in UC prognosis. Therefore, the CMV status of patients on immunosuppressants, particularly those with steroid-refractory or -dependent UC, should be tested. When CMV is detected, be performed based on should adequate treatment the extent of the viral load and the presence of certain clinical features including a large ulcer. Anti-tumor necrosis factor agents may be useful for treating CMV colitis complicating UC. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KOREAN ASSOC INTERNAL MEDICINE | - |
dc.subject | INFLAMMATORY-BOWEL-DISEASE | - |
dc.subject | HUMAN-IMMUNODEFICIENCY-VIRUS | - |
dc.subject | POLYMERASE-CHAIN-REACTION | - |
dc.subject | ANTIVIRAL THERAPY | - |
dc.subject | CROHNS-DISEASE | - |
dc.subject | GASTROINTESTINAL BIOPSIES | - |
dc.subject | ENDOSCOPIC FEATURES | - |
dc.subject | ANTIGENEMIA ASSAY | - |
dc.subject | PREVALENCE | - |
dc.subject | DIAGNOSIS | - |
dc.title | Approach to cytomegalovirus infections in patients with ulcerative colitis | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Jeen, Yoon Tae | - |
dc.identifier.doi | 10.3904/kjim.2017.087 | - |
dc.identifier.scopusid | 2-s2.0-85019905550 | - |
dc.identifier.wosid | 000401013600001 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF INTERNAL MEDICINE, v.32, no.3, pp.383 - 392 | - |
dc.relation.isPartOf | KOREAN JOURNAL OF INTERNAL MEDICINE | - |
dc.citation.title | KOREAN JOURNAL OF INTERNAL MEDICINE | - |
dc.citation.volume | 32 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 383 | - |
dc.citation.endPage | 392 | - |
dc.type.rims | ART | - |
dc.type.docType | Review | - |
dc.identifier.kciid | ART002222370 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | INFLAMMATORY-BOWEL-DISEASE | - |
dc.subject.keywordPlus | HUMAN-IMMUNODEFICIENCY-VIRUS | - |
dc.subject.keywordPlus | POLYMERASE-CHAIN-REACTION | - |
dc.subject.keywordPlus | ANTIVIRAL THERAPY | - |
dc.subject.keywordPlus | CROHNS-DISEASE | - |
dc.subject.keywordPlus | GASTROINTESTINAL BIOPSIES | - |
dc.subject.keywordPlus | ENDOSCOPIC FEATURES | - |
dc.subject.keywordPlus | ANTIGENEMIA ASSAY | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordPlus | DIAGNOSIS | - |
dc.subject.keywordAuthor | Cytomegalovirus | - |
dc.subject.keywordAuthor | Colitis | - |
dc.subject.keywordAuthor | ulcerative | - |
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