MR and mammographic imaging features of HER2-positive breast cancers according to hormone receptor status: a retrospective comparative study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Sung Eun Song | - |
dc.contributor.author | Song Sung Eun | - |
dc.date.accessioned | 2021-09-03T07:29:13Z | - |
dc.date.available | 2021-09-03T07:29:13Z | - |
dc.date.created | 2021-06-21 | - |
dc.date.issued | 2017-01 | - |
dc.identifier.issn | 0284-1851 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/83824 | - |
dc.description.abstract | Background: Human epidermal growth factor receptor 2-positive (HER2+) breast cancer has two distinct subtypes according to hormone receptor (HR) status. Survival, pattern of recurrence, and treatment response differ between HR-/HER2+ and HR+/HER2+ cancers. Purpose: To investigate imaging and clinicopathologic features of HER2+ cancers and their correlation with HR expression. Material and Methods: Between 2011 and 2013, 252 consecutive patients with 252 surgically confirmed HER2+ cancers (125 HR- and 127 HR+) were included. Two experienced breast radiologists blinded to the clinicopathologic findings reviewed the mammograms and magnetic resonance (MR) images using the BI-RADS lexicon. Tumor kinetic features were acquired by computer-aided detection (CAD). The imaging and clinicopathologic features of 125 HR-/HER2+ cancers were compared with those of 127 HR+/HER2+ cancers. Association between the HR status and each feature was assessed. Results: Multiple logistic regression analysis showed that circumscribed mass margin (odds ratio [OR], 4.73; P< 0.001), associated non-mass enhancement (NME) on MR images (OR, 3.29; P = 0.001), high histologic grade (OR, 3.89; P = 0.002), high Ki-67 index (OR, 3.06; P = 0.003), and older age (OR, 2.43; P = 0.006) remained independent indicators ass | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | SAGE PUBLICATIONS LTD | - |
dc.title | MR and mammographic imaging features of HER2-positive breast cancers according to hormone receptor status: a retrospective comparative study | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Sung Eun Song | - |
dc.contributor.affiliatedAuthor | Song Sung Eun | - |
dc.identifier.doi | 10.1177/0284185116673119 | - |
dc.identifier.bibliographicCitation | ACTA RADIOLOGICA, v.58, no.7, pp.792 - 799 | - |
dc.relation.isPartOf | ACTA RADIOLOGICA | - |
dc.citation.title | ACTA RADIOLOGICA | - |
dc.citation.volume | 58 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 792 | - |
dc.citation.endPage | 799 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordAuthor | human epidermal growth factor receptor 2 (HER2) | - |
dc.subject.keywordAuthor | hormone receptors | - |
dc.subject.keywordAuthor | mammography | - |
dc.subject.keywordAuthor | magnetic resonance imaging (MRI) | - |
dc.subject.keywordAuthor | Breast tumors | - |
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