Standard and double-dose intravenous proton pump inhibitor injections for prevention of bleeding after endoscopic resection
DC Field | Value | Language |
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dc.contributor.author | Jung, Sung Woo | - |
dc.contributor.author | Kim, Seung Young | - |
dc.contributor.author | Choe, Jung Wan | - |
dc.contributor.author | Hyun, Jong Jin | - |
dc.contributor.author | Jung, Young Kul | - |
dc.contributor.author | Koo, Ja Seol | - |
dc.contributor.author | Yim, Hyung Joon | - |
dc.contributor.author | Lee, Sang Woo | - |
dc.date.accessioned | 2021-09-03T07:50:01Z | - |
dc.date.available | 2021-09-03T07:50:01Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2017-04 | - |
dc.identifier.issn | 0815-9319 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/83971 | - |
dc.description.abstract | Background and Aim: Endoscopic resection is commonly used to remove gastric neoplasms. However, effective dosing or scheduling of proton pump inhibitors for the prevention of delayed bleeding after endoscopic resection remains unclear. Methods: One hundred sixty-six patients with gastric adenoma or early gastric cancer were enrolled. After an endoscopic procedure, each subject was randomly assigned to 40 mg every 24 h (standard dose group) or 40 mg every 12 h (double-dose group) of intravenous pantoprazole for 48 h. Second-look endoscopy was performed on day 2 after endoscopic resection to compare signs of rebleeding and ulcer status between the two groups. Result: Eighty-one patients of the standard dose group and 81 of the double-dose group were analyzed. There were no significant differences in the incidence of delayed bleeding events (1.3% vs 6.2%, P = 0.21) and bleeding ulcer at the second-look endoscopy (6.2% vs 3.9%, P = 0.69) between standard and double-dose groups. There were no other significant variables associated with delayed bleeding or bleeding ulcer on second-look endoscopy. Conclusions: Intravenous pantoprazole 40mg every 24 h or 12 h for 2 days after endoscopic resection was equally effective for the prevention of delayed bleeding. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | WILEY | - |
dc.subject | SUBMUCOSAL DISSECTION | - |
dc.subject | 2ND-LOOK ENDOSCOPY | - |
dc.subject | GASTRIC NEOPLASMS | - |
dc.subject | INTRAGASTRIC PH | - |
dc.subject | ULCER | - |
dc.subject | PANTOPRAZOLE | - |
dc.subject | HEMOSTASIS | - |
dc.subject | MANAGEMENT | - |
dc.subject | INFUSION | - |
dc.subject | TRIALS | - |
dc.title | Standard and double-dose intravenous proton pump inhibitor injections for prevention of bleeding after endoscopic resection | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Jung, Sung Woo | - |
dc.contributor.affiliatedAuthor | Kim, Seung Young | - |
dc.contributor.affiliatedAuthor | Hyun, Jong Jin | - |
dc.contributor.affiliatedAuthor | Jung, Young Kul | - |
dc.contributor.affiliatedAuthor | Koo, Ja Seol | - |
dc.contributor.affiliatedAuthor | Yim, Hyung Joon | - |
dc.contributor.affiliatedAuthor | Lee, Sang Woo | - |
dc.identifier.doi | 10.1111/jgh.13597 | - |
dc.identifier.scopusid | 2-s2.0-85016093258 | - |
dc.identifier.wosid | 000398534100010 | - |
dc.identifier.bibliographicCitation | JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, v.32, no.4, pp.778 - 781 | - |
dc.relation.isPartOf | JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY | - |
dc.citation.title | JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY | - |
dc.citation.volume | 32 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 778 | - |
dc.citation.endPage | 781 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.subject.keywordPlus | SUBMUCOSAL DISSECTION | - |
dc.subject.keywordPlus | 2ND-LOOK ENDOSCOPY | - |
dc.subject.keywordPlus | GASTRIC NEOPLASMS | - |
dc.subject.keywordPlus | INTRAGASTRIC PH | - |
dc.subject.keywordPlus | ULCER | - |
dc.subject.keywordPlus | PANTOPRAZOLE | - |
dc.subject.keywordPlus | HEMOSTASIS | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | INFUSION | - |
dc.subject.keywordPlus | TRIALS | - |
dc.subject.keywordAuthor | endoscopic resection | - |
dc.subject.keywordAuthor | iatrogenic gastric ulcer | - |
dc.subject.keywordAuthor | proton pump inhibitor | - |
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