Dynamic Circulation and Genetic Exchange of a Shrew-borne Hantavirus, Imjin virus, in the Republic of Korea
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Seung-Ho | - |
dc.contributor.author | Kim, Won-Keun | - |
dc.contributor.author | No, Jin Sun | - |
dc.contributor.author | Kim, Jeong-Ah | - |
dc.contributor.author | Kim, Jin Il | - |
dc.contributor.author | Gu, Se Hun | - |
dc.contributor.author | Kim, Heung-Chul | - |
dc.contributor.author | Klein, Terry A. | - |
dc.contributor.author | Park, Man-Seong | - |
dc.contributor.author | Song, Jin-Won | - |
dc.date.accessioned | 2021-09-03T08:22:44Z | - |
dc.date.available | 2021-09-03T08:22:44Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2017-03-15 | - |
dc.identifier.issn | 2045-2322 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/84139 | - |
dc.description.abstract | Hantaviruses (family Bunyaviridae) are enveloped negative-sense tripartite RNA viruses. The natural hosts of hantaviruses include rodents, shrews, moles, and bats. Imjin virus (MJNV) is a shrew-borne hantavirus identified from the Ussuri white-toothed shrews (Crocidura lasiura) in the Republic of Korea (ROK) and China. We have isolated MJNV and determined its prevalence and molecular diversity in Gyeonggi province, ROK. However, the distribution and phylogeography of MJNV in other regions of ROK remain unknown. A total of 96 C. lasiura were captured from Gangwon and Gyeonggi provinces, ROK, during 2011-2014. Among them, four (4.2%) shrews were positive for anti-MJNV IgG and MJNV RNA was detected from nine (9.4%), respectively. Based on the prevalence of MJNV RNA, the preponderance of infected shrews was male and adult, consistent with the gender-and weight-specific prevalence of hantaviruses in other species. We monitored the viral load of MJNV RNA in various tissues of shrews, which would reflect the dynamic infectious status and circulation of MJNV in nature. Our phylogeographic and genomic characterization of MJNV suggested natural occurrences of recombination and reassortment in the virus population. Thus, these findings provide significant insights into the epidemiology, phylogeographic diversity, and dynamic circulation and evolution of shrew-borne hantaviruses. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | NATURE PUBLISHING GROUP | - |
dc.subject | SIN-NOMBRE-VIRUS | - |
dc.subject | PULMONARY-SYNDROME | - |
dc.subject | HEMORRHAGIC-FEVER | - |
dc.subject | THOTTAPALAYAM VIRUS | - |
dc.subject | TULA HANTAVIRUS | - |
dc.subject | RENAL SYNDROME | - |
dc.subject | HANTAAN VIRUS | - |
dc.subject | RNA VIRUSES | - |
dc.subject | NEWFOUND HANTAVIRUS | - |
dc.subject | PHYLOGENETIC TREES | - |
dc.title | Dynamic Circulation and Genetic Exchange of a Shrew-borne Hantavirus, Imjin virus, in the Republic of Korea | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Jin Il | - |
dc.contributor.affiliatedAuthor | Park, Man-Seong | - |
dc.contributor.affiliatedAuthor | Song, Jin-Won | - |
dc.identifier.doi | 10.1038/srep44369 | - |
dc.identifier.scopusid | 2-s2.0-85015443996 | - |
dc.identifier.wosid | 000396330000001 | - |
dc.identifier.bibliographicCitation | SCIENTIFIC REPORTS, v.7 | - |
dc.relation.isPartOf | SCIENTIFIC REPORTS | - |
dc.citation.title | SCIENTIFIC REPORTS | - |
dc.citation.volume | 7 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.subject.keywordPlus | SIN-NOMBRE-VIRUS | - |
dc.subject.keywordPlus | PULMONARY-SYNDROME | - |
dc.subject.keywordPlus | HEMORRHAGIC-FEVER | - |
dc.subject.keywordPlus | THOTTAPALAYAM VIRUS | - |
dc.subject.keywordPlus | TULA HANTAVIRUS | - |
dc.subject.keywordPlus | RENAL SYNDROME | - |
dc.subject.keywordPlus | HANTAAN VIRUS | - |
dc.subject.keywordPlus | RNA VIRUSES | - |
dc.subject.keywordPlus | NEWFOUND HANTAVIRUS | - |
dc.subject.keywordPlus | PHYLOGENETIC TREES | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.