Significance of micrometastases in the calculation of the lymph node ratio for papillary thyroid cancer
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chang, Young Woo | - |
dc.contributor.author | Kim, Hwan Soo | - |
dc.contributor.author | Jung, Seung Pil | - |
dc.contributor.author | Kim, Hoon Yub | - |
dc.contributor.author | Lee, Jae Bok | - |
dc.contributor.author | Bae, Jeoung Won | - |
dc.contributor.author | Son, Gil Soo | - |
dc.date.accessioned | 2021-09-03T08:38:22Z | - |
dc.date.available | 2021-09-03T08:38:22Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2017-03 | - |
dc.identifier.issn | 2288-6575 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/84199 | - |
dc.description.abstract | Purpose: The lymph node ratio (LNR) is an important prognostic factor in papillary thyroid carcinoma (PTC), but micrometastases in cervical lymph nodes (LNs) are not of great clinical importance. In this study,:we analyzed the accuracy of prediction of the prognosis depending on whether micrometastases were included in the number of metastatic LNs when calculating LNR. Methods: The study included 353 PTC patients who underwent total thyroidectomy with neck LN dissection, and calculated LNR by 2 methods according to whether micrometastases were included in the number of metastatic LNs: Method 1 did not and method 2 did include. To compare the predictive values of LNR by the 2 methods, correlation coefficients and receiver operating characteristic (ROC) curves were analyzed. Results: Positive correlations were found between LNR and preablation stimulated thyroglobulin (sTg) levels in both methods, but the correlation between method 1 LNR and preablation sTg level was significantly stronger than that for method 2 (Fisher z = 1.7, P = 0.045). The areas under these 2 independent ROC curves were analyzed; the prognostic efficacy of method 1 LNR was more accurate than that of method 2 LNR, and the difference was statistically significant (P = 0.0001). Conclusion: Regional recurrence of PTC can be predicted more accurately by not including micrometastases in the number of metastatic LNs when calculating LNR. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SURGICAL SOCIETY | - |
dc.subject | CENTRAL NECK DISSECTION | - |
dc.subject | STIMULATED THYROGLOBULIN | - |
dc.subject | TUMOR SIZE | - |
dc.subject | CARCINOMA | - |
dc.subject | RECURRENCE | - |
dc.subject | METASTASIS | - |
dc.subject | PATTERN | - |
dc.subject | PREDICTOR | - |
dc.subject | THERAPY | - |
dc.subject | IMPACT | - |
dc.title | Significance of micrometastases in the calculation of the lymph node ratio for papillary thyroid cancer | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Chang, Young Woo | - |
dc.contributor.affiliatedAuthor | Jung, Seung Pil | - |
dc.contributor.affiliatedAuthor | Kim, Hoon Yub | - |
dc.contributor.affiliatedAuthor | Lee, Jae Bok | - |
dc.contributor.affiliatedAuthor | Bae, Jeoung Won | - |
dc.contributor.affiliatedAuthor | Son, Gil Soo | - |
dc.identifier.doi | 10.4174/astr.2017.92.3.117 | - |
dc.identifier.scopusid | 2-s2.0-85014860332 | - |
dc.identifier.wosid | 000396966900001 | - |
dc.identifier.bibliographicCitation | ANNALS OF SURGICAL TREATMENT AND RESEARCH, v.92, no.3, pp.117 - 122 | - |
dc.relation.isPartOf | ANNALS OF SURGICAL TREATMENT AND RESEARCH | - |
dc.citation.title | ANNALS OF SURGICAL TREATMENT AND RESEARCH | - |
dc.citation.volume | 92 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 117 | - |
dc.citation.endPage | 122 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002197118 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.subject.keywordPlus | CENTRAL NECK DISSECTION | - |
dc.subject.keywordPlus | STIMULATED THYROGLOBULIN | - |
dc.subject.keywordPlus | TUMOR SIZE | - |
dc.subject.keywordPlus | CARCINOMA | - |
dc.subject.keywordPlus | RECURRENCE | - |
dc.subject.keywordPlus | METASTASIS | - |
dc.subject.keywordPlus | PATTERN | - |
dc.subject.keywordPlus | PREDICTOR | - |
dc.subject.keywordPlus | THERAPY | - |
dc.subject.keywordPlus | IMPACT | - |
dc.subject.keywordAuthor | Papillary thyroid carcinoma | - |
dc.subject.keywordAuthor | Lymph nodes | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.