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Clinical Features of Influenza and Acute Respiratory Illness in Older Adults at Least 50 Years of Age in an Outpatient Setting in the Republic of Korea: a Prospective, Observational, Cohort Study

Authors
Kim, Woo JooLee, Jin-SooLee, Chang KyuCheong, Hee JinKim, MijeongMonegal, Javier SawchikCarneiro, RuteKyaw, Moe H.Haguinet, FrancoisRay, RijuMatias, Goncalo
Issue Date
3월-2017
Publisher
KOREAN ACAD MEDICAL SCIENCES
Keywords
Acute Respiratory Illness; Adult; Epidemiology; Influenza; Republic of Korea
Citation
JOURNAL OF KOREAN MEDICAL SCIENCE, v.32, no.3, pp.407 - +
Indexed
SCIE
SCOPUS
KCI
Journal Title
JOURNAL OF KOREAN MEDICAL SCIENCE
Volume
32
Number
3
Start Page
407
End Page
+
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/84384
DOI
10.3346/jkms.2017.32.3.407
ISSN
1011-8934
Abstract
Two prospective, multi-centre, observational studies (GlaxoSmithKline [GSK] identifier No. 110938 and 112519) were performed over 2 influenza seasons (2007-2008 and 2008-2009) in the Republic of Korea (ROK) with the aim to evaluate the burden of laboratory-confirmed influenza (LCI) in patients >= 50 years of age seeking medical attention for acute respiratory illness (ARI). The median participant age was 58 years in the 2007-2008 season and 60 years in the 2008-2009 season. LCI was observed in 101/346 (29.2%) of ARI patients in the 2007-2008 season and in 166/443 (37.5%) of ARI patients in the 20082009 season. Compared to patients with non-influenza ARI, those with LCI had higher rates of decreased daily activities (60.4% vs. 32.9% in 2007-2008 and 46.4% vs. 25.8% in 2008-2009), work absenteeism (51.1% vs. 25.6% and 14.4% vs. 7.7%), and longer duration of illness. These results indicated that influenza is an important cause of ARI in adults aged 50 and older causing more severe illness than non-influenza related ARI.
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