Left ventricular wall motion abnormalities are associated with stroke recurrence
DC Field | Value | Language |
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dc.contributor.author | Choi, Jeong-Yoon | - |
dc.contributor.author | Cha, Jaehyung | - |
dc.contributor.author | Jung, Jin-Man | - |
dc.contributor.author | Seo, Woo-Keun | - |
dc.contributor.author | Oh, Kyungmi | - |
dc.contributor.author | Cho, Kyung-Hee | - |
dc.contributor.author | Yu, Sungwook | - |
dc.date.accessioned | 2021-09-03T09:36:44Z | - |
dc.date.available | 2021-09-03T09:36:44Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2017-02-07 | - |
dc.identifier.issn | 0028-3878 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/84460 | - |
dc.description.abstract | Objective: To investigate the role of left ventricular wall motion abnormalities (LVWMA), unrelated to high-risk cardioembolic conditions, in stroke recurrence. Methods: This study included consecutive acute ischemic stroke patients. Transthoracic echocardiography was performed as a routine evaluation for stroke patients. The outcomes were the time to recurrent any stroke and ischemic stroke. Results: Among 4,316 acute ischemic stroke patients, 430 had LVWMA without high-risk cardioembolic sources. The median observation periods of patients at risk of any stroke and ischemic stroke were 24.5 and 24.7 months. During the follow-up, any stroke and ischemic stroke recurrence were observed in 310 (7.2%) and 250 (5.8%) patients. LVWMA were associated with outcomes after adjustment for traditional cardiovascular risk factors, laboratory and imaging variables, and therapeutic interventions (hazard ratio [HR] 1.707, 95% confidence interval [ CI] 1.262-2.310 for any stroke; HR 1.709, 95% CI 1.222-2.390 for ischemic stroke). Moreover, LVWMA could still be considered as independent risk factors after correction for covariates that were significantly associated with outcomes in univariable regression (HR 1.747, 95% CI 1.292-2.364 for any stroke; HR 1.704, 95% CI 1.219-2.382 for ischemic stroke). There were no significant interactions between LVWMA and outcomes between the subgroups except for the statin treatment subgroup. Conclusions: This study suggests that LVWMA, even when unassociated with high-risk cardioembolic sources, could be an independent predictor for stroke recurrence in patients with ischemic stroke. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.subject | TRANSIENT ISCHEMIC ATTACK | - |
dc.subject | ACUTE MYOCARDIAL-INFARCTION | - |
dc.subject | CARDIOEMBOLIC STROKE | - |
dc.subject | CARDIOMYOPATHY SYNDROMES | - |
dc.subject | SYSTOLIC DYSFUNCTION | - |
dc.subject | RISK-FACTORS | - |
dc.subject | FOLLOW-UP | - |
dc.subject | THROMBUS | - |
dc.subject | PREVALENCE | - |
dc.subject | ECHOCARDIOGRAPHY | - |
dc.title | Left ventricular wall motion abnormalities are associated with stroke recurrence | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Jung, Jin-Man | - |
dc.contributor.affiliatedAuthor | Oh, Kyungmi | - |
dc.contributor.affiliatedAuthor | Cho, Kyung-Hee | - |
dc.contributor.affiliatedAuthor | Yu, Sungwook | - |
dc.identifier.doi | 10.1212/wnl.0000000000003588 | - |
dc.identifier.scopusid | 2-s2.0-85011649847 | - |
dc.identifier.wosid | 000397342100014 | - |
dc.identifier.bibliographicCitation | NEUROLOGY, v.88, no.6, pp.586 - 594 | - |
dc.relation.isPartOf | NEUROLOGY | - |
dc.citation.title | NEUROLOGY | - |
dc.citation.volume | 88 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 586 | - |
dc.citation.endPage | 594 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.subject.keywordPlus | TRANSIENT ISCHEMIC ATTACK | - |
dc.subject.keywordPlus | ACUTE MYOCARDIAL-INFARCTION | - |
dc.subject.keywordPlus | CARDIOEMBOLIC STROKE | - |
dc.subject.keywordPlus | CARDIOMYOPATHY SYNDROMES | - |
dc.subject.keywordPlus | SYSTOLIC DYSFUNCTION | - |
dc.subject.keywordPlus | RISK-FACTORS | - |
dc.subject.keywordPlus | FOLLOW-UP | - |
dc.subject.keywordPlus | THROMBUS | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordPlus | ECHOCARDIOGRAPHY | - |
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