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A bioorthogonal 'turn-on' fluorescent probe for tracking mitochondrial nitroxyl formation

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dc.contributor.authorSunwoo, Kyoung-
dc.contributor.authorBobba, Kondapa Naidu-
dc.contributor.authorLim, Ja-Yun-
dc.contributor.authorPark, Taegun-
dc.contributor.authorPodder, Arup-
dc.contributor.authorHeo, June Seok-
dc.contributor.authorLee, Seung Gwan-
dc.contributor.authorBhuniya, Sankarprasad L-
dc.contributor.authorKim, Jong Seung-
dc.date.accessioned2021-09-03T09:38:17Z-
dc.date.available2021-09-03T09:38:17Z-
dc.date.created2021-06-16-
dc.date.issued2017-02-04-
dc.identifier.issn1359-7345-
dc.identifier.urihttps://scholar.korea.ac.kr/handle/2021.sw.korea/84469-
dc.description.abstractA bioreductant-resistant 'turn-on' chemodosimetric fluorescent probe Mito-1 has been developed for the detection of mitochondrial HNO in live cells. Mito-1 enables the detection of HNO as low as similar to 18 nM. It has the capability to detect both exogenous and endogenous mitochondrial HNO formations in cellular milieus by providing fluorescence images. Its two-photon imaging ability fosters its use as a non-invasive imaging tool for the detection of mitochondrial nitroxyl.-
dc.languageEnglish-
dc.language.isoen-
dc.publisherROYAL SOC CHEMISTRY-
dc.subjectLIVING CELLS-
dc.subjectNITRIC-OXIDE-
dc.subjectREDUCTANT-RESISTANT-
dc.subjectBIOLOGICAL NITROXYL-
dc.subjectAQUEOUS-SOLUTION-
dc.subjectIN-VIVO-
dc.subjectHNO-
dc.subjectCHEMODOSIMETER-
dc.subjectTISSUES-
dc.subjectMETABOLISM-
dc.titleA bioorthogonal 'turn-on' fluorescent probe for tracking mitochondrial nitroxyl formation-
dc.typeArticle-
dc.contributor.affiliatedAuthorLee, Seung Gwan-
dc.contributor.affiliatedAuthorKim, Jong Seung-
dc.identifier.doi10.1039/c6cc09082f-
dc.identifier.scopusid2-s2.0-85011016401-
dc.identifier.wosid000395441400038-
dc.identifier.bibliographicCitationCHEMICAL COMMUNICATIONS, v.53, no.10, pp.1723 - 1726-
dc.relation.isPartOfCHEMICAL COMMUNICATIONS-
dc.citation.titleCHEMICAL COMMUNICATIONS-
dc.citation.volume53-
dc.citation.number10-
dc.citation.startPage1723-
dc.citation.endPage1726-
dc.type.rimsART-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalWebOfScienceCategoryChemistry, Multidisciplinary-
dc.subject.keywordPlusLIVING CELLS-
dc.subject.keywordPlusNITRIC-OXIDE-
dc.subject.keywordPlusREDUCTANT-RESISTANT-
dc.subject.keywordPlusBIOLOGICAL NITROXYL-
dc.subject.keywordPlusAQUEOUS-SOLUTION-
dc.subject.keywordPlusIN-VIVO-
dc.subject.keywordPlusHNO-
dc.subject.keywordPlusCHEMODOSIMETER-
dc.subject.keywordPlusTISSUES-
dc.subject.keywordPlusMETABOLISM-
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