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Endoscopic micro-optical coherence tomography with extended depth of focus using a binary phase spatial filter

Authors
Kim, JunyoungXing, JingchaoNam, Hyeong SooSong, Joon WooKim, Jin WonYoo, Hongki
Issue Date
1-2월-2017
Publisher
OPTICAL SOC AMER
Citation
OPTICS LETTERS, v.42, no.3, pp.379 - 382
Indexed
SCIE
SCOPUS
Journal Title
OPTICS LETTERS
Volume
42
Number
3
Start Page
379
End Page
382
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/84497
DOI
10.1364/OL.42.000379
ISSN
0146-9592
Abstract
Micro-optical coherence tomography (mu OCT) is an advanced imaging technique that acquires a three-dimensional microstructure of biological samples with a high spatial resolution, up to 1 mu m, by using a broadband light source and a high numerical aperture (NA) lens. As high NA produces a short depth of focus (DOF), extending the DOF is necessary to obtain a reasonable imaging depth. However, due to the complexity of optics and the limited space, it has been challenging to fabricate endoscopic mu OCT, which is essential for clinical translation. Here, we report an endoscopic mu OCT probe with an extended DOF by using a binary phase spatial filter. The imaging results from latex beads demonstrated that the mu OCT probe achieved an axial resolution of 2.49 mu m and a lateral resolution of 2.59 mu m with a DOF extended by a factor of 2. The feasibility of clinical use was demonstrated by ex vivo imaging of the rabbit iliac artery. (C) 2017 Optical Society of America.
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