The effect of nicardipine on the surgical pleth index during thyroidectomy under general anesthesia A prospective double-blind randomized controlled trial
DC Field | Value | Language |
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dc.contributor.author | Won, Young Ju | - |
dc.contributor.author | Lim, Byung Gun | - |
dc.contributor.author | Yeo, Gwi Eun | - |
dc.contributor.author | Lee, Min Ki | - |
dc.contributor.author | Lee, Dong Kyu | - |
dc.contributor.author | Kim, Heezoo | - |
dc.contributor.author | Lee, Il Ok | - |
dc.contributor.author | Kong, Myoung Hoon | - |
dc.date.accessioned | 2021-09-03T10:34:26Z | - |
dc.date.available | 2021-09-03T10:34:26Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2017-02 | - |
dc.identifier.issn | 0025-7974 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/84824 | - |
dc.description.abstract | Background: The effectiveness of surgical pleth index (SPI) for managing nociception-antinociception balance during general anesthesia with vasodilators, including nicardipine has not been demonstrated. We aimed to compare the time course during surgery in SPI values in patients receiving nicardipine or remifentanil infusion during thyroidectomy. Methods: Forty patients undergoing thyroidectomy were randomly assigned to receive nicardipine (group N; n=19) or remifentanil (group R; n=21) along with induction (propofol, fentanyl, and rocuronium) and maintenance (50% desflurane/nitrous oxide in oxygen) anesthesia (goal bispectral index [BIS] similar to 50). The infusion of nicardipine or remifentanil was started before the 1st incision and adjusted to keep mean blood pressure (MBP) within +/- 20% of the preoperative value. SPI, BIS, end-tidal desflurane concentration (EtDes), MBP, and heart rate were recorded at 2.5 minute intervals from the 1st incision to the end of surgery. Extubation and recovery times, pain score/rescue ketorolac consumption, and adverse events in postanesthesia care unit (PACU) were recorded. Results: The trend of SPI during surgery was comparable between the 2 groups (P=0.804), although the heart rates in group N were significantly higher than those in group R (P=0.040). The patient characteristics, trends of BIS, EtDes, and MBP during surgery, extubation and recovery times, and incidence of nausea/vomiting were comparable between the groups. Group N had significantly lower pain scores and rescue ketorolac consumption at PACU. Conclusion: SPI was comparable between patients receiving nicardipine or remifentanil infusion during thyroidectomy under general anesthesia, which suggests that the administration of nicardipine may confound the interpretation of SPI values during general anesthesia. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.subject | STRESS INDEX | - |
dc.subject | GUIDED ANALGESIA | - |
dc.subject | REMIFENTANIL ANESTHESIA | - |
dc.subject | CONVENTIONAL ANALGESIA | - |
dc.subject | SEVOFLURANE ANESTHESIA | - |
dc.subject | BALANCE | - |
dc.subject | PAIN | - |
dc.subject | CONSUMPTION | - |
dc.subject | INFUSION | - |
dc.subject | RECOVERY | - |
dc.title | The effect of nicardipine on the surgical pleth index during thyroidectomy under general anesthesia A prospective double-blind randomized controlled trial | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lim, Byung Gun | - |
dc.contributor.affiliatedAuthor | Lee, Dong Kyu | - |
dc.contributor.affiliatedAuthor | Kim, Heezoo | - |
dc.contributor.affiliatedAuthor | Kong, Myoung Hoon | - |
dc.identifier.doi | 10.1097/MD.0000000000006154 | - |
dc.identifier.scopusid | 2-s2.0-85013952826 | - |
dc.identifier.wosid | 000394391200056 | - |
dc.identifier.bibliographicCitation | MEDICINE, v.96, no.6 | - |
dc.relation.isPartOf | MEDICINE | - |
dc.citation.title | MEDICINE | - |
dc.citation.volume | 96 | - |
dc.citation.number | 6 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | STRESS INDEX | - |
dc.subject.keywordPlus | GUIDED ANALGESIA | - |
dc.subject.keywordPlus | REMIFENTANIL ANESTHESIA | - |
dc.subject.keywordPlus | CONVENTIONAL ANALGESIA | - |
dc.subject.keywordPlus | SEVOFLURANE ANESTHESIA | - |
dc.subject.keywordPlus | BALANCE | - |
dc.subject.keywordPlus | PAIN | - |
dc.subject.keywordPlus | CONSUMPTION | - |
dc.subject.keywordPlus | INFUSION | - |
dc.subject.keywordPlus | RECOVERY | - |
dc.subject.keywordAuthor | analgesics | - |
dc.subject.keywordAuthor | calcium channel blocker | - |
dc.subject.keywordAuthor | nicardipine | - |
dc.subject.keywordAuthor | opioid | - |
dc.subject.keywordAuthor | pulse oximetry | - |
dc.subject.keywordAuthor | remifentanil | - |
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