Detailed Information

Cited 0 time in webofscience Cited 0 time in scopus
Metadata Downloads

The utility of bispectral index monitoring for prevention of rocuronium-induced withdrawal movement in children A randomized controlled trial

Authors
Lim, Byung GunLee, Il OkKim, Young SungWon, Young JuKim, HeezooKong, Myoung Hoon
Issue Date
1월-2017
Publisher
LIPPINCOTT WILLIAMS & WILKINS
Keywords
anesthesia; anesthesia; anesthetics; bispectral index monitor; children; general; inhalation; rocuronium; sevoflurane; thiopental
Citation
MEDICINE, v.96, no.2
Indexed
SCIE
SCOPUS
Journal Title
MEDICINE
Volume
96
Number
2
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/85061
DOI
10.1097/MD.0000000000005871
ISSN
0025-7974
Abstract
Background: This study was designed to determine whether a deep hypnotic state with a bispectral index (BIS) value less than 40 could alleviate withdrawal movement (WM) upon rocuronium injection during anesthesia induction in children. Methods: Finally, 135 healthy children (3-12 years) scheduled for minor elective surgery were studied. Without premedication, anesthesia was induced with thiopental sodium 5mg/kg. Patients were randomized into 2 groups (control vs experimental) and then by virtue of rocuronium injection time, patients in the experimental group were allocated into 2 groups, as follows: in the control group (group C; n=45), rocuronium 0.6mg/kg was administered at the loss of eyelash reflex; in the 1st experimental group, rocuronium 0.6 mg/kg was administered when BIS fell to less than 40 (group T; n=45); however, if BIS did not fall below 40 after thiopental sodium administration, manual ventilation was provided with oxygen 6L/minute using sevoflurane 8% and then rocuronium was administered when BIS fell below 40 (the 2nd experimental group, group S; n=45). Rocuronium-inducedWMwas evaluated using a 4-point scale (no movement; movement/withdrawal involving the arm only; generalized response, with movement/withdrawal of more than 1 extremity, but no requirement for restraint of the body; and generalized response which required restraint of the body and caused coughing or breath-holding). Results: No significant differences were found among the groups for patient characteristics including age, sex, height, and location of venous cannula. However, body weight, height, and body mass index in group S were all smaller than those in group T. The incidence ofWM caused by rocuronium was 100% in group C, 95.6% in group T, and 80% in group S, and was significantly lower in group S than in group C. The grade ofWMwas 3.7 +/- 0.6 in group C, 3.2 +/- 0.9 in group T, and 2.6 +/- 1.0 in group S. It was significantly lower in group T than in group C and significantly lower in group S than in groups C and T. Conclusion: The confirmation of a deep hypnotic state with BIS values lower than 40 using BIS monitoring can reduce the grade of rocuronium-induced WMs during anesthesia induction using thiopental sodium or sevoflurane in children.
Files in This Item
There are no files associated with this item.
Appears in
Collections
College of Medicine > Department of Medical Science > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Lee, Il Ok photo

Lee, Il Ok
의과대학 (의학과)
Read more

Altmetrics

Total Views & Downloads

BROWSE