Duration of Pulmonary Tuberculosis Infectiousness under Adequate Therapy, as Assessed Using Induced Sputum Samples
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ko, Yousang | - |
dc.contributor.author | Shin, Jeong Hwan | - |
dc.contributor.author | Lee, Hyun-Kyung | - |
dc.contributor.author | Lee, Young Seok | - |
dc.contributor.author | Lee, Suh-Young | - |
dc.contributor.author | Park, So Young | - |
dc.contributor.author | Mo, Eun-Kyung | - |
dc.contributor.author | Kim, Changhwan | - |
dc.contributor.author | Park, Yong Bum | - |
dc.date.accessioned | 2021-09-03T11:32:57Z | - |
dc.date.available | 2021-09-03T11:32:57Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2017-01 | - |
dc.identifier.issn | 1738-3536 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/85070 | - |
dc.description.abstract | Background: A sputum culture is the most reliable indicator of the infectiousness of pulmonary tuberculosis (PTB); however, a spontaneous sputum specimen may not be suitable. The aim of this study was to evaluate the infectious period in patients with non-drug-resistant (DR) PTB receiving adequate standard chemotherapy, using induced sputum (IS) specimens. Methods: We evaluated the duration of infectiousness of PTB using a retrospective cohort design. Results: Among the 35 patients with PTB, 22 were smear-positive. The rates of IS culture positivity from baseline to the sixth week of anti-tuberculosis medication in the smear-positive PTB group were 100%, 100%, 91%, 73%, 36%, and 18%, respectively. For smear-positive PTB cases, the median time of conversion to culture negativity was 35.0 days (range, 28.0-42.0 days). In the smear-negative PTB group (n=13), the weekly rates of positive IS culture were 100%, 77%, 39%, 8%, 0%, and 0%, respectively, and the median time to conversion to culture-negative was 21.0 days (range, 17.5-28.0 days). Conclusion: The infectiousness of PTB, under adequate therapy, may persist longer than previously reported, even in patients with non-DR PTB. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | TAEHAN KYORHAEK HYOPHOE-KOREAN ACAD TUBERCULOSIS & RESPIRATORY DISEASES | - |
dc.subject | TRANSMISSION | - |
dc.subject | DIAGNOSIS | - |
dc.subject | INDUCTION | - |
dc.subject | INFECTIVITY | - |
dc.subject | MICROSCOPY | - |
dc.subject | CONVERSION | - |
dc.subject | CULTURE | - |
dc.subject | COUGH | - |
dc.subject | TIME | - |
dc.title | Duration of Pulmonary Tuberculosis Infectiousness under Adequate Therapy, as Assessed Using Induced Sputum Samples | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Young Seok | - |
dc.identifier.doi | 10.4046/trd.2017.80.1.27 | - |
dc.identifier.scopusid | 2-s2.0-85009936542 | - |
dc.identifier.wosid | 000406830300004 | - |
dc.identifier.bibliographicCitation | TUBERCULOSIS AND RESPIRATORY DISEASES, v.80, no.1, pp.27 - 34 | - |
dc.relation.isPartOf | TUBERCULOSIS AND RESPIRATORY DISEASES | - |
dc.citation.title | TUBERCULOSIS AND RESPIRATORY DISEASES | - |
dc.citation.volume | 80 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 27 | - |
dc.citation.endPage | 34 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002184419 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Respiratory System | - |
dc.relation.journalWebOfScienceCategory | Respiratory System | - |
dc.subject.keywordPlus | TRANSMISSION | - |
dc.subject.keywordPlus | DIAGNOSIS | - |
dc.subject.keywordPlus | INDUCTION | - |
dc.subject.keywordPlus | INFECTIVITY | - |
dc.subject.keywordPlus | MICROSCOPY | - |
dc.subject.keywordPlus | CONVERSION | - |
dc.subject.keywordPlus | CULTURE | - |
dc.subject.keywordPlus | COUGH | - |
dc.subject.keywordPlus | TIME | - |
dc.subject.keywordAuthor | Tuberculosis, Pulmonary | - |
dc.subject.keywordAuthor | Mycobacterium tuberculosis | - |
dc.subject.keywordAuthor | Infectious Disease Incubation Period | - |
dc.subject.keywordAuthor | Induced Sputum | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.