Paraproteinemic neuropathyParaproteinemic neuropathy
- Other Titles
- Paraproteinemic neuropathy
- Authors
- 변소영; 김병조
- Issue Date
- 2017
- Publisher
- 대한임상신경생리학회
- Keywords
- Monoclonal gammopathy; Paraproteins; Peripheral neuropathy; POEMS Syndrome; Multiple myeloma; Waldenstrom macroglobulinemia
- Citation
- Annals of Clinical Neurophysiology, v.19, no.2, pp.79 - 92
- Indexed
- KCI
- Journal Title
- Annals of Clinical Neurophysiology
- Volume
- 19
- Number
- 2
- Start Page
- 79
- End Page
- 92
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/85838
- DOI
- 10.14253/acn.2017.19.2.79
- ISSN
- 2508-691X
- Abstract
- Paraproteinemia is caused by a proliferation of monoclonal plasma cells or B lymphocytes. Approximately 10% of idiopathic neuropathies are associated with paraproteinemia, where a certain paraprotein acts like an antibody targeted at constituents of myelin or axolemma in peripheral nerves. The relationship between paraproteinemia and peripheral neuropathy remains unclear despite this being of interest for a long time. Neurologists frequently find paraproteinemia during laboratory examinations of patients presenting with peripheral neuropathy, especially in the elderly. The possibility of a relationship with paraproteinemia should be considered in cases without an explainable cause. We review the causal association between paraproteinemia and neuropathy as well as clinical, laboratory, and electrophysiologic features, and the treatment options for paraproteinemic neuropathy.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
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