Effects of Different doses of Silk Peptide on Energy Metabolism During Exercise in MiceEffects of Different doses of Silk Peptide on Energy Metabolism During Exercise in Mice
- Other Titles
- Effects of Different doses of Silk Peptide on Energy Metabolism During Exercise in Mice
- Authors
- 김지수; 박종훈; 김보경; 이치호; 임기원; 서혜정
- Issue Date
- 2017
- Publisher
- 한국운동영양학회
- Keywords
- Silk peptide; Energy metabolism; Exercise; Dose-response.
- Citation
- Physical Activity and Nutrition, v.21, no.1, pp.21 - 25
- Journal Title
- Physical Activity and Nutrition
- Volume
- 21
- Number
- 1
- Start Page
- 21
- End Page
- 25
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/85860
- DOI
- 10.20463/jenb.2017.0056
- Abstract
- [Purpose] This study was carried out to determine the optimal dose of silk peptide for enhancing fat metabolism during exercise.
[Methods] Fifty male ICR mice were randomly divided into five groups: Sed, SP0, SP200, SP400, and SP800. All SP mice underwent training by running on a treadmill 5 times a week for 2 weeks (20 m/min, 8° slope, 50 min/day for the first week and 25 m/min, 8° slope, 50 min/day at about 70-75% of maximum oxygen uptake for the second week).
[Results] After the 2 weeks, fat oxidation was measured during a 1-h exercise at the training conditions of the second week and was found to be 1.02 ± 0.15, 1.04 ± 0.17, 0.98 ± 0.10, 1.14 ± 0.19, and 1.15 ± 0.07 g/kg/ h for Sed, SP0, SP200, SP400, and SP800 groups, respectively. The SP800 group had significantly higher fat oxidation levels than the SP0 group did at 36, 40, and 56 min and the Sed group did at 2, 4, 6, 8, 12, 14, 16, 20, 40, 46, 50, 52, 56, and 60 min. However, there was no significant difference among the groups in carbohydrate oxidation during the 1-h exercise. SP doses of 200 mg/kg and 400 mg/kg did not show any effect on fat and carbohydrate oxidation.
[Conclusion] In conclusion, 800 mg/kg of silk peptide is the optimal dose for enhancing fat metabolism during exercise. In addition, silk peptide treatment could reduce body weight by enhancing fat metabolism.
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