Comparison of in vivo antibacterial and antithrombotic activities of two types of pulmonary artery catheters in pig
- Authors
- Han, J.W.; Shin, Y.S.; Kim, J.J.; Son, H.S.
- Issue Date
- 2017
- Publisher
- BioMed Central Ltd.
- Keywords
- Infection; Pig; Pulmonary artery catheter; Thrombosis
- Citation
- Biomaterials Research, v.21, no.1
- Indexed
- SCOPUS
KCI
- Journal Title
- Biomaterials Research
- Volume
- 21
- Number
- 1
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/86093
- DOI
- 10.1186/s40824-017-0109-3
- ISSN
- 2055-7124
- Abstract
- Background: During pulmonary artery catheter (PAC) implantation, inaccurate measurements of hemodynamic parameters due to infection or thrombosis of PAC can result in severe complications. Method: In order to develop a new PAC material, we evaluated the antibacterial and antithrombotic activities of the two types of PAC (Swan Ganz catheter and prototype catheter) in 14 pigs. Results: In the 3-day group, bacterial infection rate was not different between the two types of PAC. In the 7-day group, bacterial infection rate of the prototype catheter was twice as elevated as that of the Swan-Ganz catheter. In the 3-day group, thrombus formation rate of the prototype catheter was twice as elevated as that of the Swan-Ganz catheter. In the 7-day group, thrombus formation rate was the same for the two types of PAC. Conclusion: Here, we report an experimental pig model that confirms differences in antibacterial and antithrombotic activities. © 2017 The Author(s).
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
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