Endothelial Glycocalyx as Biomarker for Cardiovascular Diseases: Mechanistic and Clinical Implications
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Y.-H. | - |
dc.contributor.author | Nijst, P. | - |
dc.contributor.author | Kiefer, K. | - |
dc.contributor.author | Tang, W.H.W. | - |
dc.date.accessioned | 2021-09-03T14:03:23Z | - |
dc.date.available | 2021-09-03T14:03:23Z | - |
dc.date.created | 2021-06-17 | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 1546-9530 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/86099 | - |
dc.description.abstract | Introduction: The endothelial surface layer is covered with abundant proteoglycans, of which syndecans and glycosaminoglycans are major constituents. Recent Findings: Among the endothelial glycocalyx (eGC) constituents, syndecan-1 (sdc1) is a main component, and an elevated serum level of sdc1 may indicate the degradation of eGC. In patients with ischemic heart disease or heart failure, elevation of serum sdc1 has been associated with worsening cardiac and renal function; however, the causal relationship between degradation of eGC and clinical outcomes is unclear. Summary: Herein, we review the previous literature on eGC in cardiovascular and noncardiovascular diseases and their clinical implications. © 2017, Springer Science+Business Media New York. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | Current Science Inc. | - |
dc.subject | acetylcysteine | - |
dc.subject | amino terminal pro brain natriuretic peptide | - |
dc.subject | biological marker | - |
dc.subject | glycosaminoglycan | - |
dc.subject | heparin | - |
dc.subject | intercellular adhesion molecule 1 | - |
dc.subject | low density lipoprotein cholesterol | - |
dc.subject | syndecan 1 | - |
dc.subject | tumor necrosis factor | - |
dc.subject | vasculotropin | - |
dc.subject | biological marker | - |
dc.subject | syndecan 1 | - |
dc.subject | area under the curve | - |
dc.subject | blood vessel permeability | - |
dc.subject | cardiovascular disease | - |
dc.subject | cell proliferation | - |
dc.subject | endothelial dysfunction | - |
dc.subject | flow-mediated dilation test | - |
dc.subject | fluorescence microscopy | - |
dc.subject | glycocalyx | - |
dc.subject | heart function | - |
dc.subject | Hodgkin disease | - |
dc.subject | human | - |
dc.subject | kidney function | - |
dc.subject | nonhuman | - |
dc.subject | protein expression | - |
dc.subject | Review | - |
dc.subject | blood | - |
dc.subject | cardiovascular disease | - |
dc.subject | chemistry | - |
dc.subject | glycocalyx | - |
dc.subject | heart failure | - |
dc.subject | heart muscle ischemia | - |
dc.subject | metabolism | - |
dc.subject | vascular endothelium | - |
dc.subject | Biomarkers | - |
dc.subject | Cardiovascular Diseases | - |
dc.subject | Endothelium, Vascular | - |
dc.subject | Glycocalyx | - |
dc.subject | Heart Failure | - |
dc.subject | Humans | - |
dc.subject | Myocardial Ischemia | - |
dc.subject | Syndecan-1 | - |
dc.title | Endothelial Glycocalyx as Biomarker for Cardiovascular Diseases: Mechanistic and Clinical Implications | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Y.-H. | - |
dc.identifier.doi | 10.1007/s11897-017-0320-5 | - |
dc.identifier.scopusid | 2-s2.0-85013646787 | - |
dc.identifier.bibliographicCitation | Current Heart Failure Reports, v.14, no.2, pp.117 - 126 | - |
dc.relation.isPartOf | Current Heart Failure Reports | - |
dc.citation.title | Current Heart Failure Reports | - |
dc.citation.volume | 14 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 117 | - |
dc.citation.endPage | 126 | - |
dc.type.rims | ART | - |
dc.type.docType | Review | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordPlus | acetylcysteine | - |
dc.subject.keywordPlus | amino terminal pro brain natriuretic peptide | - |
dc.subject.keywordPlus | biological marker | - |
dc.subject.keywordPlus | glycosaminoglycan | - |
dc.subject.keywordPlus | heparin | - |
dc.subject.keywordPlus | intercellular adhesion molecule 1 | - |
dc.subject.keywordPlus | low density lipoprotein cholesterol | - |
dc.subject.keywordPlus | syndecan 1 | - |
dc.subject.keywordPlus | tumor necrosis factor | - |
dc.subject.keywordPlus | vasculotropin | - |
dc.subject.keywordPlus | biological marker | - |
dc.subject.keywordPlus | syndecan 1 | - |
dc.subject.keywordPlus | area under the curve | - |
dc.subject.keywordPlus | blood vessel permeability | - |
dc.subject.keywordPlus | cardiovascular disease | - |
dc.subject.keywordPlus | cell proliferation | - |
dc.subject.keywordPlus | endothelial dysfunction | - |
dc.subject.keywordPlus | flow-mediated dilation test | - |
dc.subject.keywordPlus | fluorescence microscopy | - |
dc.subject.keywordPlus | glycocalyx | - |
dc.subject.keywordPlus | heart function | - |
dc.subject.keywordPlus | Hodgkin disease | - |
dc.subject.keywordPlus | human | - |
dc.subject.keywordPlus | kidney function | - |
dc.subject.keywordPlus | nonhuman | - |
dc.subject.keywordPlus | protein expression | - |
dc.subject.keywordPlus | Review | - |
dc.subject.keywordPlus | blood | - |
dc.subject.keywordPlus | cardiovascular disease | - |
dc.subject.keywordPlus | chemistry | - |
dc.subject.keywordPlus | glycocalyx | - |
dc.subject.keywordPlus | heart failure | - |
dc.subject.keywordPlus | heart muscle ischemia | - |
dc.subject.keywordPlus | metabolism | - |
dc.subject.keywordPlus | vascular endothelium | - |
dc.subject.keywordPlus | Biomarkers | - |
dc.subject.keywordPlus | Cardiovascular Diseases | - |
dc.subject.keywordPlus | Endothelium, Vascular | - |
dc.subject.keywordPlus | Glycocalyx | - |
dc.subject.keywordPlus | Heart Failure | - |
dc.subject.keywordPlus | Humans | - |
dc.subject.keywordPlus | Myocardial Ischemia | - |
dc.subject.keywordPlus | Syndecan-1 | - |
dc.subject.keywordAuthor | Cardiovascular diseases | - |
dc.subject.keywordAuthor | Endothelial glycocalyx | - |
dc.subject.keywordAuthor | Syndecan-1 (sdc1) | - |
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