Suicidal thoughts/acts and clinical correlates in patients with depressive disorders in Asians: results from the REAP-AD study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Seon-Cheol | - |
dc.contributor.author | Lee, Min-Soo | - |
dc.contributor.author | Hahn, Sang Woo | - |
dc.contributor.author | Si, Tian-Mei | - |
dc.contributor.author | Kanba, Shigenobu | - |
dc.contributor.author | Chong, Mian-Yoon | - |
dc.contributor.author | Yoon, Chee Kok | - |
dc.contributor.author | Udomratn, Pichet | - |
dc.contributor.author | Tripathi, Adarsh | - |
dc.contributor.author | Sartorius, Norman | - |
dc.contributor.author | Shinfuku, Naotaka | - |
dc.contributor.author | Maramis, Margarita M. | - |
dc.contributor.author | Park, Yong Chon | - |
dc.date.accessioned | 2021-09-03T16:02:28Z | - |
dc.date.available | 2021-09-03T16:02:28Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2016-12 | - |
dc.identifier.issn | 0924-2708 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/86592 | - |
dc.description.abstract | Objective: Using data from the Research on Asian Psychotropic Prescription Patterns for Antidepressants (REAP-AD) study, we aimed to present the rates and clinical correlates of suicidal thoughts/acts in patients recruited from a total of 40 centres in 10 Asian countries/areas: China, Hong Kong, India, Indonesia, Japan, Korea, Malaysia, Singapore, Taiwan, and Thailand. Methods: Data from 1122 patients with depressive disorders in the REAP-AD study were used. The ICD-10 was employed to diagnose depressive episodes and recurrent depressive disorder. The presence or absence of suicidal thoughts/acts and profile of other depressive symptoms was established using the National Institute for Health and Clinical Excellence guidelines for depression. Country/area differences in rates of suicidal thoughts/acts were evaluated with the chi(2) test. In addition, depressive symptom profiles, other clinical characteristics, and patterns of psychotropic drug prescription in depressed patients with and without suicidal thoughts/acts were compared using analysis of covariance for continuous variables and logistic regression analysis for discrete variables to adjust the effects of covariates. Results: The rates of suicidal thoughts/acts in 10 countries/areas varied from 12.8% in Japan to 36.3% in China. Patients with suicidal thoughts/acts presented more persistent sadness (adjusted odds ratio [aOR] = 2.64, p<0.001), loss of interest (aOR = 2.33, p<0.001), fatigue (aOR = 1.58, p<0.001), insomnia (aOR = 1.74, p<0.001), poor concentration (aOR = 1.88, p<0.001), low self-confidence (aOR = 1.78, p<0.001), poor appetite (aOR = 2.27, p<0.001), guilt/self-blame (aOR = 3.03, p<0.001), and use of mood stabilisers (aOR = 1.79, p<0.001) than those without suicidal thoughts/acts. Conclusion: Suicidal thoughts/acts can indicate greater severity of depression, and are associated with a poorer response to antidepressants and increased burden of illness. Hence, suicidal thoughts/acts can provide a clinical index reflecting the clinical status of depressive disorders in Asians. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | CAMBRIDGE UNIV PRESS | - |
dc.subject | PSYCHOTROPIC PRESCRIPTION PATTERNS | - |
dc.subject | RISK-FACTORS | - |
dc.subject | IDEATION | - |
dc.subject | SYMPTOMS | - |
dc.subject | ANTIDEPRESSANTS | - |
dc.subject | OUTPATIENTS | - |
dc.subject | COUNTRIES | - |
dc.subject | HEALTH | - |
dc.subject | SAMPLE | - |
dc.title | Suicidal thoughts/acts and clinical correlates in patients with depressive disorders in Asians: results from the REAP-AD study | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Min-Soo | - |
dc.identifier.doi | 10.1017/neu.2016.27 | - |
dc.identifier.scopusid | 2-s2.0-84975167811 | - |
dc.identifier.wosid | 000387823800005 | - |
dc.identifier.bibliographicCitation | ACTA NEUROPSYCHIATRICA, v.28, no.6, pp.337 - 345 | - |
dc.relation.isPartOf | ACTA NEUROPSYCHIATRICA | - |
dc.citation.title | ACTA NEUROPSYCHIATRICA | - |
dc.citation.volume | 28 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 337 | - |
dc.citation.endPage | 345 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalResearchArea | Psychiatry | - |
dc.relation.journalWebOfScienceCategory | Neurosciences | - |
dc.relation.journalWebOfScienceCategory | Psychiatry | - |
dc.subject.keywordPlus | PSYCHOTROPIC PRESCRIPTION PATTERNS | - |
dc.subject.keywordPlus | RISK-FACTORS | - |
dc.subject.keywordPlus | IDEATION | - |
dc.subject.keywordPlus | SYMPTOMS | - |
dc.subject.keywordPlus | ANTIDEPRESSANTS | - |
dc.subject.keywordPlus | OUTPATIENTS | - |
dc.subject.keywordPlus | COUNTRIES | - |
dc.subject.keywordPlus | HEALTH | - |
dc.subject.keywordPlus | SAMPLE | - |
dc.subject.keywordAuthor | Asians | - |
dc.subject.keywordAuthor | depressive disorders | - |
dc.subject.keywordAuthor | mood stabilisers | - |
dc.subject.keywordAuthor | suicidal thoughts/acts | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.