Top-down and bottom-up neurodynamic evidence in patients with tinnitus
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Hong, Sung Kwang | - |
dc.contributor.author | Park, Sejik | - |
dc.contributor.author | Ahn, Min-Hee | - |
dc.contributor.author | Min, Byoung-Kyong | - |
dc.date.accessioned | 2021-09-03T16:22:18Z | - |
dc.date.available | 2021-09-03T16:22:18Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2016-12 | - |
dc.identifier.issn | 0378-5955 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/86702 | - |
dc.description.abstract | Although a peripheral auditory (bottom-up) deficit is an essential prerequisite for the generation of tinnitus, central cognitive (top-down) impairment has also been shown to be an inherent neuropathological mechanism. Using an auditory oddball paradigm (for top-down analyses) and a passive listening paradigm (for bottom-up analyses) while recording electroencephalograms (EEGs), we investigated whether top-down or bottom-up components were more critical in the neuropathology of tinnitus, independent of peripheral hearing loss. We observed significantly reduced P300 amplitudes (reflecting fundamental cognitive processes such as attention) and evoked theta power (reflecting top-down regulation in memory systems) for target stimuli at the tinnitus frequency of patients with tinnitus but without hearing loss. The contingent negative variation (reflecting top-down expectation of a subsequent event prior to stimulation) and N100 (reflecting auditory bottom-up selective attention) were different between the healthy and patient groups. Interestingly, when tinnitus patients were divided into two subgroups based on their P300 amplitudes, their P170 and N200 components, and annoyance and distress indices to their tinnitus sound were different. EEG theta-band power and its Granger causal neurodynamic results consistently support a double dissociation of these two groups in both top-down and bottom-up tasks. Directed cortical connectivity corroborates that the tinnitus network involves the anterior cingulate and the parahippocampal areas, where higher-order top-down control is generated. Together, our observations provide neurophysiological and neurodynamic evidence revealing a differential engagement of top-down impairment along with deficits in bottom-up processing in patients with tinnitus but without hearing loss. (C) 2016 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE BV | - |
dc.subject | ANTERIOR CINGULATE CORTEX | - |
dc.subject | HIGH-RESOLUTION EEG | - |
dc.subject | CORTICAL POTENTIAL DISTRIBUTION | - |
dc.subject | DORSOLATERAL PREFRONTAL CORTEX | - |
dc.subject | CONTINGENT NEGATIVE-VARIATION | - |
dc.subject | DIRECTED TRANSFER-FUNCTION | - |
dc.subject | HIGH-FREQUENCY AUDIOMETRY | - |
dc.subject | PRIMARY AUDITORY-CORTEX | - |
dc.subject | FALSE DISCOVERY RATE | - |
dc.subject | WORKING-MEMORY TASK | - |
dc.title | Top-down and bottom-up neurodynamic evidence in patients with tinnitus | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Min, Byoung-Kyong | - |
dc.identifier.doi | 10.1016/j.heares.2016.10.002 | - |
dc.identifier.scopusid | 2-s2.0-84994388369 | - |
dc.identifier.wosid | 000389398700009 | - |
dc.identifier.bibliographicCitation | HEARING RESEARCH, v.342, pp.86 - 100 | - |
dc.relation.isPartOf | HEARING RESEARCH | - |
dc.citation.title | HEARING RESEARCH | - |
dc.citation.volume | 342 | - |
dc.citation.startPage | 86 | - |
dc.citation.endPage | 100 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Audiology & Speech-Language Pathology | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalResearchArea | Otorhinolaryngology | - |
dc.relation.journalWebOfScienceCategory | Audiology & Speech-Language Pathology | - |
dc.relation.journalWebOfScienceCategory | Neurosciences | - |
dc.relation.journalWebOfScienceCategory | Otorhinolaryngology | - |
dc.subject.keywordPlus | ANTERIOR CINGULATE CORTEX | - |
dc.subject.keywordPlus | HIGH-RESOLUTION EEG | - |
dc.subject.keywordPlus | CORTICAL POTENTIAL DISTRIBUTION | - |
dc.subject.keywordPlus | DORSOLATERAL PREFRONTAL CORTEX | - |
dc.subject.keywordPlus | CONTINGENT NEGATIVE-VARIATION | - |
dc.subject.keywordPlus | DIRECTED TRANSFER-FUNCTION | - |
dc.subject.keywordPlus | HIGH-FREQUENCY AUDIOMETRY | - |
dc.subject.keywordPlus | PRIMARY AUDITORY-CORTEX | - |
dc.subject.keywordPlus | FALSE DISCOVERY RATE | - |
dc.subject.keywordPlus | WORKING-MEMORY TASK | - |
dc.subject.keywordAuthor | Attention | - |
dc.subject.keywordAuthor | Causality | - |
dc.subject.keywordAuthor | Electroencephalogram | - |
dc.subject.keywordAuthor | Top-down | - |
dc.subject.keywordAuthor | Tinnitus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
145 Anam-ro, Seongbuk-gu, Seoul, 02841, Korea+82-2-3290-2963
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.