Detection of Silver Ions Using Dielectrophoretic Tweezers-Based Force Spectroscopy
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Choi, Seungyeop | - |
dc.contributor.author | Lee, Gyudo | - |
dc.contributor.author | Park, In Soo | - |
dc.contributor.author | Son, Myeonggu | - |
dc.contributor.author | Kim, Woong | - |
dc.contributor.author | Lee, Hyungbeen | - |
dc.contributor.author | Lee, Sei-Young | - |
dc.contributor.author | Na, Sungsoo | - |
dc.contributor.author | Yoon, Dae Sung | - |
dc.contributor.author | Bashir, Rashid | - |
dc.contributor.author | Park, Jinsung | - |
dc.contributor.author | Lee, Sang Woo | - |
dc.date.accessioned | 2021-09-03T16:56:45Z | - |
dc.date.available | 2021-09-03T16:56:45Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2016-11-15 | - |
dc.identifier.issn | 0003-2700 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/86824 | - |
dc.description.abstract | Understanding of the interactions of silver ions (Ag+) with polynucleotides is important not only to detect Ag+ over a wide range of concentrations in a simple, robust, and high-throughput manner but also to investigate the intermolecular interactions of hydrogen and coordinate interactions that are generated due to the interplay of Ag+, hydrogen ions (H+), and polynucleotides since it is critical to prevent adverse environmental effects that may cause DNA damage and develop strategies to treat this damage. Here, we demonstrate a novel approach to simultaneously detect Ag+ satisfying the above requirements and examine the combined intermolecular interactions of Ag+-polycytosine and H+-polycytosine DNA complexes using dielectrophoretic tweezers-based force spectroscopy. For this investigation, we detected Ag+ over a range of concentrations (1 nM to 100 mu M) by quantifying the rupture force of the combined interactions and examined the interplay between the three factors (Ag+, H+, and polycytosine) using the same assay for the detection of Ag+. Our study provides a new avenue not only for the detection of heavy metal ions but also for the investigation of heavy metal ions-polynucleotide DNA complexes using the same assay. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.subject | I-MOTIF | - |
dc.subject | SELECTIVE DETECTION | - |
dc.subject | OPTICAL TWEEZERS | - |
dc.subject | NUCLEIC-ACIDS | - |
dc.subject | DUPLEX DNA | - |
dc.subject | NANOPARTICLES | - |
dc.subject | PROBE | - |
dc.subject | AG+ | - |
dc.subject | BINDING | - |
dc.subject | PAIRS | - |
dc.title | Detection of Silver Ions Using Dielectrophoretic Tweezers-Based Force Spectroscopy | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Gyudo | - |
dc.contributor.affiliatedAuthor | Na, Sungsoo | - |
dc.contributor.affiliatedAuthor | Yoon, Dae Sung | - |
dc.contributor.affiliatedAuthor | Park, Jinsung | - |
dc.identifier.doi | 10.1021/acs.analchem.6b00107 | - |
dc.identifier.scopusid | 2-s2.0-85018312727 | - |
dc.identifier.wosid | 000388154700017 | - |
dc.identifier.bibliographicCitation | ANALYTICAL CHEMISTRY, v.88, no.22, pp.10867 - 10875 | - |
dc.relation.isPartOf | ANALYTICAL CHEMISTRY | - |
dc.citation.title | ANALYTICAL CHEMISTRY | - |
dc.citation.volume | 88 | - |
dc.citation.number | 22 | - |
dc.citation.startPage | 10867 | - |
dc.citation.endPage | 10875 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.subject.keywordPlus | I-MOTIF | - |
dc.subject.keywordPlus | SELECTIVE DETECTION | - |
dc.subject.keywordPlus | OPTICAL TWEEZERS | - |
dc.subject.keywordPlus | NUCLEIC-ACIDS | - |
dc.subject.keywordPlus | DUPLEX DNA | - |
dc.subject.keywordPlus | NANOPARTICLES | - |
dc.subject.keywordPlus | PROBE | - |
dc.subject.keywordPlus | AG+ | - |
dc.subject.keywordPlus | BINDING | - |
dc.subject.keywordPlus | PAIRS | - |
dc.subject.keywordAuthor | Silver ion detection | - |
dc.subject.keywordAuthor | dielectrophoresis | - |
dc.subject.keywordAuthor | DEP tweezers | - |
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