Changes in antibiotic resistance in recurrent Pseudomonas aeruginosa infections of chronic suppurative otitis media
- Authors
- Song, Jae-Jun; Lee, Byung Don; Lee, Koen Hyeong; Lee, Jong Dae; Park, Young Joo; Park, Moo Kyun
- Issue Date
- 10월-2016
- Publisher
- VENDOME GROUP LLC
- Citation
- ENT-EAR NOSE & THROAT JOURNAL, v.95, no.10-11, pp.446 - 451
- Indexed
- SCIE
SCOPUS
- Journal Title
- ENT-EAR NOSE & THROAT JOURNAL
- Volume
- 95
- Number
- 10-11
- Start Page
- 446
- End Page
- 451
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/87249
- ISSN
- 0145-5613
- Abstract
- This study investigated the changes in antibiotic resistance in recurrent Pseudomonas aeruginosa infections in chronic suppurative otitis media (CSOM). Its aim was to provide a treatment strategy for P aeruginosa infections in CSOM for the prevention of multidrug resistance. A case control study was conducted in tertiary teachinghospitals in Korea. The experimental group included patients with recurrent P aeruginosa infection who had relapsed within 2 months after the successful control of a previous P aeruginosa infection. The control group consisted of patients with a P aeruginosa infection who had no history of such an infection. An antibiotic sensitivity test was performed for each culture. The proportion ofrecurrentP aeruginosa infection was 22.69% (98 of 432 cases). Drug resistance to amikacin, tobramycin, netilmicin, ciprofloxacin, and levofloxacin was significantly changed after recurrent infection. The fluoroquinolone strains seen in recurrent P aeruginosa showed high cross-resistance to other drugs. Antibiotic resistance of P aeruginosa in CSOM changed with recurrent infection.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
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