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Research Update: Nanoscale surface potential analysis of MoS2 field-effect transistors for biomolecular detection using Kelvin probe force microscopy
- Authors
- Kim, Min Hyung; Park, Heekyeong; Lee, Hyungbeen; Nam, Kihwan; Jeong, Seokhwan; Omkaram, Inturu; Yoon, Dae Sung; Lee, Sei Young; Kim, Sunkook; Lee, Sang Woo
- Issue Date
- 10월-2016
- Publisher
- AMER INST PHYSICS
- Keywords
- MoS2 FET; KPFM; surface potential; biosensor
- Citation
- APL MATERIALS, v.4, no.10
- Indexed
- SCIE
SCOPUS
- Journal Title
- APL MATERIALS
- Volume
- 4
- Number
- 10
- ISSN
- 2166-532X
- Abstract
- We used high-resolution Kelvin probe force microscopy (KPFM) to investigate the immobilization of a prostate specific antigen (PSA) antibody by measuring the surface potential (SP) on a MoS2 surface over an extensive concentration range (1 pg/ml-100 mu g/ml). After PSA antibody immobilization, we demonstrated that the SP on the MoS2 surface characterized by KPFM strongly correlated to the electrical signal of a MoS2 bioFET. This demonstration can not only be used to optimize the immobilization conditions for captured molecules, but can also be applied as a diagnostic tool to complement the electrical detection of a MoS2 FET biosensor. (C) 2016 Author(s).
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Collections - Graduate School > Department of Bioengineering > 1. Journal Articles
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