A Human Serum-Based Enzyme-Free Continuous Glucose Monitoring Technique Using a Needle-Type Bio-Layer Interference Sensor
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Seo, Dongmin | - |
dc.contributor.author | Paek, Sung-Ho | - |
dc.contributor.author | Oh, Sangwoo | - |
dc.contributor.author | Seo, Sungkyu | - |
dc.contributor.author | Paek, Se-Hwan | - |
dc.date.accessioned | 2021-09-03T19:35:09Z | - |
dc.date.available | 2021-09-03T19:35:09Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2016-10 | - |
dc.identifier.issn | 1424-8220 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/87410 | - |
dc.description.abstract | The incidence of diabetes is continually increasing, and by 2030, it is expected to have increased by 69% and 20% in underdeveloped and developed countries, respectively. Therefore, glucose sensors are likely to remain in high demand in medical device markets. For the current study, we developed a needle-type bio-layer interference (BLI) sensor that can continuously monitor glucose levels. Using dialysis procedures, we were able to obtain hypoglycemic samples from commercial human serum. These dialysis-derived samples, alongside samples of normal human serum were used to evaluate the utility of the sensor for the detection of the clinical interest range of glucose concentrations (70-200 mg/dL), revealing high system performance for a wide glycemic state range (45-500 mg/dL). Reversibility and reproducibility were also tested over a range of time spans. Combined with existing BLI system technology, this sensor holds great promise for use as a wearable online continuous glucose monitoring system for patients in a hospital setting. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | MDPI | - |
dc.subject | BIOSENSOR | - |
dc.title | A Human Serum-Based Enzyme-Free Continuous Glucose Monitoring Technique Using a Needle-Type Bio-Layer Interference Sensor | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Seo, Sungkyu | - |
dc.contributor.affiliatedAuthor | Paek, Se-Hwan | - |
dc.identifier.doi | 10.3390/s16101581 | - |
dc.identifier.scopusid | 2-s2.0-84988731392 | - |
dc.identifier.wosid | 000386131600034 | - |
dc.identifier.bibliographicCitation | SENSORS, v.16, no.10 | - |
dc.relation.isPartOf | SENSORS | - |
dc.citation.title | SENSORS | - |
dc.citation.volume | 16 | - |
dc.citation.number | 10 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalResearchArea | Instruments & Instrumentation | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.relation.journalWebOfScienceCategory | Engineering, Electrical & Electronic | - |
dc.relation.journalWebOfScienceCategory | Instruments & Instrumentation | - |
dc.subject.keywordPlus | BIOSENSOR | - |
dc.subject.keywordAuthor | continuous glucose monitoring | - |
dc.subject.keywordAuthor | competitive assay | - |
dc.subject.keywordAuthor | glucose dialysis method | - |
dc.subject.keywordAuthor | bio-layer interferometry | - |
dc.subject.keywordAuthor | needle-type sensor | - |
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