Radiofrequency Catheter Ablation Improves the Quality of Life Measured with a Short Form-36 Questionnaire in Atrial Fibrillation Patients: A Systematic Review and Meta-Analysis
- Authors
- Kim, Yun Gi; Shim, Jaemin; Choi, Jong-Il; Kim, Young-Hoon
- Issue Date
- 28-9월-2016
- Publisher
- PUBLIC LIBRARY SCIENCE
- Citation
- PLOS ONE, v.11, no.9
- Indexed
- SCIE
SCOPUS
- Journal Title
- PLOS ONE
- Volume
- 11
- Number
- 9
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/87481
- DOI
- 10.1371/journal.pone.0163755
- ISSN
- 1932-6203
- Abstract
- Background The main purpose of performing radiofrequency catheter ablation (RFCA) in atrial fibrillation (AF) patients is to improve the quality of life (QoL) and alleviate AF-related symptoms. We aimed to determine the qualitative and quantitative effects of RFCA on the QoL in AF patients. Methods We performed a systemic review and meta-analysis using a random effects model. We searched for the studies that reported the physical component summary score (PCS) and mental component summary score (MCS) of the short form-36, a validated system to assess and quantify the QoL, before and after RFCA in AF patients. PCS and MCS are T-scores with a mean of 50 and standard deviation of 10. Results Of the 470 studies identified through systematic search, we included 13 studies for pre-RFCA vs. the post-RFCA analysis and 5 studies for treatment success vs. AF recurrence analyses. In the pre-RFCA vs. post-RFCA analysis, RFCA was associated with a significant increase in both the PCS (weighted mean difference [WMD] = 6.33 [4.81-7.84]; p < 0.001) and MCS (WMD = 7.80 [6.15-9.44]; p < 0.001). The Delta PCS (post-RFCA PCS-pre-RFCA PCS) and Delta MCS values were used for the treatment success vs. AF recurrence analysis. Patients with successful ablation had a higher Delta PCS (WMD = 7.46 [4.44-10.49]; p < 0.001) and Delta MCS (WMD = 7.59 [4.94-10.24]; p < 0.001). Conclusions RFCA is associated with a significant increase in the PCS and MCS in AF patients. Patients without AF recurrence after RFCA had a better improvement in the PCS and MCS than patients who had AF recurrence.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
- Graduate School > Department of Biomedical Sciences > 1. Journal Articles
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