Opportunistic diseases among HIV-infected patients: a multicenter-nationwide Korean HIV/AIDS cohort study, 2006 to 2013
DC Field | Value | Language |
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dc.contributor.author | Kim, Youn Jeong | - |
dc.contributor.author | Woo, Jun Hee | - |
dc.contributor.author | Kim, Min Ja | - |
dc.contributor.author | Park, Dae Won | - |
dc.contributor.author | Song, Joon-Young | - |
dc.contributor.author | Kim, Shin Woo | - |
dc.contributor.author | Choi, Jun Yong | - |
dc.contributor.author | Kim, June Myung | - |
dc.contributor.author | Han, Sang Hoon | - |
dc.contributor.author | Lee, Jin-Soo | - |
dc.contributor.author | Choi, Bo Youl | - |
dc.contributor.author | Lee, Joo Shil | - |
dc.contributor.author | Kim, Sung-Soon | - |
dc.contributor.author | Kee, Mee-Kyung | - |
dc.contributor.author | Kang, Moon Won | - |
dc.contributor.author | Kim, Sang Il | - |
dc.date.accessioned | 2021-09-03T20:41:28Z | - |
dc.date.available | 2021-09-03T20:41:28Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2016-09 | - |
dc.identifier.issn | 1226-3303 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/87708 | - |
dc.description.abstract | Background/Aims: The frequencies of opportunistic diseases (ODs) vary across countries based on genetic, environmental, and social differences. The Korean HIV/AIDS cohort study was initiated in 2006 to promote research on human immunodeficiency virus (HIV) infection in Korea, and to provide a logistical network to support multicenter projects on epidemiological, clinical, and laboratory aspects of HIV infection. This study evaluated the prevalence of ODs among HIV-infected patients in the era of highly active antiretroviral therapy, and the risk factors associated with ODs. Methods: The study enrolled 1,086 HIV-infected patients from 19 hospitals. This study examined the baseline data of the HIV/AIDS Korean cohort study at the time of enrollment from December 2006 to July 2013. Results: Candidiasis was the most prevalent opportunistic infection (n = 176, 16.2%), followed by Mycobacterium tuberculosis infection (n = 120, 10.9%), Pneumocystis jirovecii pneumonia (n = 121, 11.0%), cytomegalovirus infection (n = 52, 4.7%), and herpes zoster (n = 44, 4.0%). The prevalence rates of Kaposi's sarcoma (n = 8, 0.7%) and toxoplasmosis (n = 4, 0.4%) were very low compared with other countries. The risk factors for ODs were a low CD4 T cell count at the time of HIV diagnosis (odds ratio [ OR], 1.01; p < 0.01), current smoking (OR, 2.27; p = 0.01), current alcohol use (OR, 2.57; p = 0.04), and a history of tuberculosis (OR, 5.23; p < 0.01). Conclusions: Using recent Korean nationwide data, this study demonstrated that an important predictor of ODs was a low CD4 T cell count at the time of HIV diagnosis. Tuberculosis remains one of the most important ODs in HIV-infected patients in Korea. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KOREAN ASSOC INTERNAL MEDICINE | - |
dc.subject | ACTIVE ANTIRETROVIRAL THERAPY | - |
dc.subject | RISK-FACTORS | - |
dc.subject | ORAL CANDIDIASIS | - |
dc.subject | TUBERCULOSIS | - |
dc.subject | INITIATION | - |
dc.subject | ILLNESSES | - |
dc.subject | EPIDEMIOLOGY | - |
dc.title | Opportunistic diseases among HIV-infected patients: a multicenter-nationwide Korean HIV/AIDS cohort study, 2006 to 2013 | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Min Ja | - |
dc.contributor.affiliatedAuthor | Park, Dae Won | - |
dc.contributor.affiliatedAuthor | Song, Joon-Young | - |
dc.identifier.doi | 10.3904/kjim.2014.322 | - |
dc.identifier.scopusid | 2-s2.0-84986879576 | - |
dc.identifier.wosid | 000383669400017 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF INTERNAL MEDICINE, v.31, no.5, pp.953 - 960 | - |
dc.relation.isPartOf | KOREAN JOURNAL OF INTERNAL MEDICINE | - |
dc.citation.title | KOREAN JOURNAL OF INTERNAL MEDICINE | - |
dc.citation.volume | 31 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 953 | - |
dc.citation.endPage | 960 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002144266 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | ACTIVE ANTIRETROVIRAL THERAPY | - |
dc.subject.keywordPlus | RISK-FACTORS | - |
dc.subject.keywordPlus | ORAL CANDIDIASIS | - |
dc.subject.keywordPlus | TUBERCULOSIS | - |
dc.subject.keywordPlus | INITIATION | - |
dc.subject.keywordPlus | ILLNESSES | - |
dc.subject.keywordPlus | EPIDEMIOLOGY | - |
dc.subject.keywordAuthor | AIDS-related opportunistic infections | - |
dc.subject.keywordAuthor | HIV | - |
dc.subject.keywordAuthor | Korea | - |
dc.subject.keywordAuthor | Tuberculosis | - |
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