Short-Term Outcomes of Endoscopic Submucosal Dissection in Patients with Early Gastric Cancer: A Prospective Multicenter Cohort Study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Choi, Ii Ju | - |
dc.contributor.author | Lee, Na Rae | - |
dc.contributor.author | Kim, Sang Gyun | - |
dc.contributor.author | Lee, Wan Sik | - |
dc.contributor.author | Park, Seun Ja | - |
dc.contributor.author | Kim, Jae J. | - |
dc.contributor.author | Lee, Jun Haeng | - |
dc.contributor.author | Kwon, Jin-Won | - |
dc.contributor.author | Park, Seung-Hee | - |
dc.contributor.author | You, Ji Hye | - |
dc.contributor.author | Kim, Ji Hyun | - |
dc.contributor.author | Lim, Chul-Hyun | - |
dc.contributor.author | Cho, Joo Young | - |
dc.contributor.author | Kim, Gwang Ha | - |
dc.contributor.author | Lee, Yong Chan | - |
dc.contributor.author | Jung, Hwoon-Yong | - |
dc.contributor.author | Kim, Ji Young | - |
dc.contributor.author | Chun, Hoon Jai | - |
dc.contributor.author | Seol, Sang-Yong | - |
dc.date.accessioned | 2021-09-03T20:57:32Z | - |
dc.date.available | 2021-09-03T20:57:32Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2016-09 | - |
dc.identifier.issn | 1976-2283 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/87770 | - |
dc.description.abstract | Background/Aims: Endoscopic submucosal dissection (ESD) is an effective treatment for early gastric cancer (EGC) that has demonstrated a minimal risk of lymph node metastasis in retrospective studies. We sought to prospectively evaluate the short-term outcomes of ESD treatment in EGCs. Methods: A prospective multicenter cohort study of neoplasms 3 cm or less in diameter at endoscopic size evaluation was performed in 12 Korean ESD study group related university hospitals and the National Cancer Center. Resected specimens were evaluated by the central pathologic review board. Results: A patient cohort (n=712) with a total of 737 EGCs was analyzed. The margin-free en bloc resection rate was 97.3%, and curative resection of 640 lesions (86.8%) was achieved. Lower curative resection rates were associated with lesions 2 to 3 cm in size prior to ESD compared with lesions 2 cm or less in size (78.6% vs 88.1%, respectively, p=0.009). Significant factors associated with noncurative resection were moderately or poorly differentiated histological type, posterior wall tumor location, tumor size larger than 3 cm, ulceration, and submucosal invasion. Delayed bleeding occurred in 49 patients (6.9%), and 12 patients (1.7%) exhibited perforations. Conclusions: ESD is an effective treatment with a high curative resection rate for EGCs that meets relatively conservative pre-ESD indications. Long-term survival outcomes should be evaluated in followup studies. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | EDITORIAL OFFICE GUT & LIVER | - |
dc.subject | CLINICAL-OUTCOMES | - |
dc.subject | HELICOBACTER-PYLORI | - |
dc.subject | CURATIVE RESECTION | - |
dc.subject | MUCOSAL RESECTION | - |
dc.subject | BALLOON DILATION | - |
dc.subject | LEARNING-CURVE | - |
dc.subject | RISK-FACTORS | - |
dc.subject | EMR | - |
dc.subject | RECURRENCE | - |
dc.subject | CURABILITY | - |
dc.title | Short-Term Outcomes of Endoscopic Submucosal Dissection in Patients with Early Gastric Cancer: A Prospective Multicenter Cohort Study | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Chun, Hoon Jai | - |
dc.identifier.doi | 10.5009/gnl15466 | - |
dc.identifier.scopusid | 2-s2.0-84990046581 | - |
dc.identifier.wosid | 000382422700014 | - |
dc.identifier.bibliographicCitation | GUT AND LIVER, v.10, no.5, pp.739 - 748 | - |
dc.relation.isPartOf | GUT AND LIVER | - |
dc.citation.title | GUT AND LIVER | - |
dc.citation.volume | 10 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 739 | - |
dc.citation.endPage | 748 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002144597 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.subject.keywordPlus | CLINICAL-OUTCOMES | - |
dc.subject.keywordPlus | HELICOBACTER-PYLORI | - |
dc.subject.keywordPlus | CURATIVE RESECTION | - |
dc.subject.keywordPlus | MUCOSAL RESECTION | - |
dc.subject.keywordPlus | BALLOON DILATION | - |
dc.subject.keywordPlus | LEARNING-CURVE | - |
dc.subject.keywordPlus | RISK-FACTORS | - |
dc.subject.keywordPlus | EMR | - |
dc.subject.keywordPlus | RECURRENCE | - |
dc.subject.keywordPlus | CURABILITY | - |
dc.subject.keywordAuthor | Stomach neoplasms | - |
dc.subject.keywordAuthor | Endoscopy | - |
dc.subject.keywordAuthor | gastrointestinal | - |
dc.subject.keywordAuthor | Outcome assess | - |
dc.subject.keywordAuthor | Prospective studies | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.