Diffusion-Induced Hydrophilic Conversion of Polydimethylsiloxane/Block-Type Phospholipid Polymer Hybrid Substrate for Temporal Cell-Adhesive Surface
DC Field | Value | Language |
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dc.contributor.author | Seo, Ji-Hun | - |
dc.contributor.author | Ishihara, Kazuhiko | - |
dc.date.accessioned | 2021-09-03T21:00:40Z | - |
dc.date.available | 2021-09-03T21:00:40Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2016-08-24 | - |
dc.identifier.issn | 1944-8244 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/87790 | - |
dc.description.abstract | In this study, diffusion-induced hydrophobic hydrophilic conversion of the surface of the cross-linked polydimethylsiloxane (PDMS) substrate was realized by employing a simple swelling-deswelling process of PDMS substrate in a block-type polymer solution with the aim of development of a temporal cell adhesive substrate. The ABA block-type polymer composed of poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) segment and PDMS segment with over 70% of dimethylsiloxane unit composition could be successfully incorporated in the PDMS substrate during the swelling-deswelling process to prepare the PDMS/phospholipid block copolymer hybrid substrates. During the aging process of the PDMS substrate for 4 days in aqueous medium, its surface property changed gradually from hydrophobic to hydrophilic. X-ray photoelectron spectroscopy and atomic force microscopy data provided strong evidence that the time-dependent hydrophilic conversion of the PDMS/block-type phospholipid polymer hybrid substrate was induced by the diffusion of the hydrophilic PMPC segment in the block-type polymer to be tethered on the substrate. During the hydrophilic conversion process, surface-adsorbed fibronectin was gradually desorbed from the substrate surface, and this resulted in successful detachment of two-dimensional connected cell crowds. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.subject | TRANSFER RADICAL POLYMERIZATION | - |
dc.subject | PROTEIN ADSORPTION | - |
dc.subject | EXTRACELLULAR-MATRIX | - |
dc.subject | PLATELET-ADHESION | - |
dc.subject | FIBRONECTIN | - |
dc.subject | POLY(DIMETHYLSILOXANE) | - |
dc.subject | RECONSTRUCTION | - |
dc.subject | BINDING | - |
dc.subject | TISSUES | - |
dc.subject | FATE | - |
dc.title | Diffusion-Induced Hydrophilic Conversion of Polydimethylsiloxane/Block-Type Phospholipid Polymer Hybrid Substrate for Temporal Cell-Adhesive Surface | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Seo, Ji-Hun | - |
dc.identifier.doi | 10.1021/acsami.6b07414 | - |
dc.identifier.scopusid | 2-s2.0-84983480765 | - |
dc.identifier.wosid | 000382179400083 | - |
dc.identifier.bibliographicCitation | ACS APPLIED MATERIALS & INTERFACES, v.8, no.33, pp.21839 - 21846 | - |
dc.relation.isPartOf | ACS APPLIED MATERIALS & INTERFACES | - |
dc.citation.title | ACS APPLIED MATERIALS & INTERFACES | - |
dc.citation.volume | 8 | - |
dc.citation.number | 33 | - |
dc.citation.startPage | 21839 | - |
dc.citation.endPage | 21846 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.subject.keywordPlus | TRANSFER RADICAL POLYMERIZATION | - |
dc.subject.keywordPlus | PROTEIN ADSORPTION | - |
dc.subject.keywordPlus | EXTRACELLULAR-MATRIX | - |
dc.subject.keywordPlus | PLATELET-ADHESION | - |
dc.subject.keywordPlus | FIBRONECTIN | - |
dc.subject.keywordPlus | POLY(DIMETHYLSILOXANE) | - |
dc.subject.keywordPlus | RECONSTRUCTION | - |
dc.subject.keywordPlus | BINDING | - |
dc.subject.keywordPlus | TISSUES | - |
dc.subject.keywordPlus | FATE | - |
dc.subject.keywordAuthor | poly(2-methacryloyloxyethyl phosphorylcholine) | - |
dc.subject.keywordAuthor | polydimethylsiloxane | - |
dc.subject.keywordAuthor | swelling-deswelling process | - |
dc.subject.keywordAuthor | hybrid material | - |
dc.subject.keywordAuthor | cell adhesion | - |
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