Surgical Margin Does Not Influence Recurrence Rate in pT1 Clear Cell Renal Cell Carcinoma After Partial Nephrectomy: A Multicenter Study
DC Field | Value | Language |
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dc.contributor.author | Kang, Ho Won | - |
dc.contributor.author | Lee, Sang Keun | - |
dc.contributor.author | Kim, Won Tae | - |
dc.contributor.author | Yun, Seok Joong | - |
dc.contributor.author | Lee, Sang-Cheol | - |
dc.contributor.author | Kim, Wun-Jae | - |
dc.contributor.author | Hwang, Eu Chang | - |
dc.contributor.author | Kang, Seok Ho | - |
dc.contributor.author | Hong, Sung-Hoo | - |
dc.contributor.author | Chung, Jinsoo | - |
dc.contributor.author | Kwon, Tae Gyun | - |
dc.contributor.author | Kim, Hyeon Hoe | - |
dc.contributor.author | Kwak, Cheol | - |
dc.contributor.author | Byun, Seok-Soo | - |
dc.contributor.author | Kim, Yong-June | - |
dc.date.accessioned | 2021-09-03T22:09:22Z | - |
dc.date.available | 2021-09-03T22:09:22Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2016-07-01 | - |
dc.identifier.issn | 0022-4790 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/88097 | - |
dc.description.abstract | Purpose: To assess the risk factors of positive surgical margins (PSM) and the influence of margin status on recurrence in pT1 clear cell renal cell carcinoma (RCC) following partial nephrectomy (PN). Materials and Methods: Patients (1,831) with pathologically confirmed stage T1 clear cell RCC were retrospectively analyzed following PN at eight institutions in Korea between 1999 and 2011. Demographics, operative data, pathological margin status, and site of recurrence were analyzed. Results: Resection margins were positive in 31 patients (1.7% of the cohort) on final pathology. None of the clinicopathological parameters were significantly related to the marginal status (all P > 0.05). During a median follow-up of 32.5 months, local recurrences were observed in 0.4% of negative surgical margins. There was no local recurrence in any of the cases with PSM. Distant recurrences developed in 1.7% of negative surgical margins and 3.2% of PSM. There were no significant differences in recurrence-free survival by margin status (P = 0.566). Conclusions: Our multi-institutional data suggest that marginal status does not influence tumor recurrence risk in pT1 clear cell RCC after PN. Careful surveillance seems to be a sufficient strategy in this clinical scenario. (C) 2016 Wiley Periodicals, Inc. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | WILEY-BLACKWELL | - |
dc.subject | NEPHRON-SPARING SURGERY | - |
dc.subject | LAPAROSCOPIC PARTIAL NEPHRECTOMY | - |
dc.subject | ONCOLOGICAL OUTCOMES | - |
dc.subject | FOLLOW-UP | - |
dc.subject | IMPACT | - |
dc.subject | GUIDELINES | - |
dc.subject | MANAGEMENT | - |
dc.subject | CANCER | - |
dc.subject | TUMORS | - |
dc.title | Surgical Margin Does Not Influence Recurrence Rate in pT1 Clear Cell Renal Cell Carcinoma After Partial Nephrectomy: A Multicenter Study | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kang, Seok Ho | - |
dc.identifier.doi | 10.1002/jso.24259 | - |
dc.identifier.scopusid | 2-s2.0-84976551485 | - |
dc.identifier.wosid | 000383777600012 | - |
dc.identifier.bibliographicCitation | JOURNAL OF SURGICAL ONCOLOGY, v.114, no.1, pp.70 - 74 | - |
dc.relation.isPartOf | JOURNAL OF SURGICAL ONCOLOGY | - |
dc.citation.title | JOURNAL OF SURGICAL ONCOLOGY | - |
dc.citation.volume | 114 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 70 | - |
dc.citation.endPage | 74 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Oncology | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalWebOfScienceCategory | Oncology | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.subject.keywordPlus | NEPHRON-SPARING SURGERY | - |
dc.subject.keywordPlus | LAPAROSCOPIC PARTIAL NEPHRECTOMY | - |
dc.subject.keywordPlus | ONCOLOGICAL OUTCOMES | - |
dc.subject.keywordPlus | FOLLOW-UP | - |
dc.subject.keywordPlus | IMPACT | - |
dc.subject.keywordPlus | GUIDELINES | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | CANCER | - |
dc.subject.keywordPlus | TUMORS | - |
dc.subject.keywordAuthor | partial nephrectomy | - |
dc.subject.keywordAuthor | recurrence | - |
dc.subject.keywordAuthor | margin | - |
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