First-Generation Versus Second-Generation Drug-Eluting Stents in Coronary Chronic Total Occlusions: Two-Year Results of a Multicenter Registry
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ahn, Jong-Hwa | - |
dc.contributor.author | Yang, Jeong Hoon | - |
dc.contributor.author | Yu, Cheol Woong | - |
dc.contributor.author | Kim, Je Sang | - |
dc.contributor.author | Lee, Hyun Jong | - |
dc.contributor.author | Choi, Rak Kyeong | - |
dc.contributor.author | Kim, Tae Hoon | - |
dc.contributor.author | Jang, Ho Joon | - |
dc.contributor.author | Choi, Young Jin | - |
dc.contributor.author | Roh, Young Moo | - |
dc.contributor.author | Shim, Won-Heum | - |
dc.contributor.author | Bin Song, Young | - |
dc.contributor.author | Hahn, Joo-Yong | - |
dc.contributor.author | Choi, Jin-Ho | - |
dc.contributor.author | Lee, Sang Hoon | - |
dc.contributor.author | Gwon, Hyeon-Cheol | - |
dc.contributor.author | Choi, Seung-Hyuk | - |
dc.date.accessioned | 2021-09-03T22:51:28Z | - |
dc.date.available | 2021-09-03T22:51:28Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2016-06-17 | - |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/88324 | - |
dc.description.abstract | Background Limited data are available regarding the long-term clinical outcomes of second-generation drug-eluting stents (DES) versus first-generation DES in patients with coronary chronic total occlusion (CTO) who undergo percutaneous coronary intervention (PCI). The aim of this study was to compare the clinical outcomes of second-generation DES with those of first-generation DES for the treatment of CTO. Methods and Results Between March 2003 and February 2012, 1,006 consecutive patients with CTO who underwent successful PCI using either first-generation DES (n = 557) or second-generation DES (n = 449) were enrolled in a multicenter, observational registry. Propensity-score matching was also performed. The primary outcome was cardiac death over a 2-year follow-up period. No significant differences were observed between the two groups regarding the incidence of cardiac death (first-generation DES versus second-generation DES; 2.5% vs 2.0%; hazard ratio [HR]: 0.86; 95% confidence interval [CI]: 0.37 to 1.98; p = 0.72) or major adverse cardiac events (MACE, 11.8% vs 11.4%; HR: 1.00; 95% CI: 0.67 to 1.50; p = 0.99). After propensity score matching, the incidences of cardiac death (HR: 0.86; 95% CI: 0.35 to 2.06; p = 0.86) and MACE (HR: 0.93; 95% CI: 0.63 to 1.37; p = 0.71) were still similar in both groups. Furthermore, no significant differences were observed between sirolimus-eluting, paclitaxel-eluting, zotarolimus-eluting, and everolimus-eluting stents regarding the incidence of cardiac death or MACE. Conclusion This study shows that the efficacy of second-generation DES is comparable to that of first-generation DES for treatment of CTO over 2 years of follow-up. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | PUBLIC LIBRARY SCIENCE | - |
dc.subject | RANDOMIZED CONTROLLED-TRIAL | - |
dc.subject | CONSENSUS DOCUMENT | - |
dc.subject | FOLLOW-UP | - |
dc.subject | PERCUTANEOUS RECANALIZATION | - |
dc.subject | BALLOON ANGIOPLASTY | - |
dc.subject | SIROLIMUS | - |
dc.subject | EVEROLIMUS | - |
dc.subject | ARTERIES | - |
dc.subject | OUTCOMES | - |
dc.subject | INTERVENTION | - |
dc.title | First-Generation Versus Second-Generation Drug-Eluting Stents in Coronary Chronic Total Occlusions: Two-Year Results of a Multicenter Registry | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Yu, Cheol Woong | - |
dc.identifier.doi | 10.1371/journal.pone.0157549 | - |
dc.identifier.scopusid | 2-s2.0-84976310120 | - |
dc.identifier.wosid | 000378030000033 | - |
dc.identifier.bibliographicCitation | PLOS ONE, v.11, no.6 | - |
dc.relation.isPartOf | PLOS ONE | - |
dc.citation.title | PLOS ONE | - |
dc.citation.volume | 11 | - |
dc.citation.number | 6 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.subject.keywordPlus | RANDOMIZED CONTROLLED-TRIAL | - |
dc.subject.keywordPlus | CONSENSUS DOCUMENT | - |
dc.subject.keywordPlus | FOLLOW-UP | - |
dc.subject.keywordPlus | PERCUTANEOUS RECANALIZATION | - |
dc.subject.keywordPlus | BALLOON ANGIOPLASTY | - |
dc.subject.keywordPlus | SIROLIMUS | - |
dc.subject.keywordPlus | EVEROLIMUS | - |
dc.subject.keywordPlus | ARTERIES | - |
dc.subject.keywordPlus | OUTCOMES | - |
dc.subject.keywordPlus | INTERVENTION | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.