Detailed Information

Cited 0 time in webofscience Cited 0 time in scopus
Metadata Downloads

Identification of D-amino acid dehydrogenase as an upstream regulator of the autoinduction of a putative acyltransferase in Corynebacterium glutamicum

Authors
Lee, Jung-HoonKim, Yong-JaeShin, Hee-SungLee, Heung-ShickJin, ShouguangHa, Un-Hwan
Issue Date
6월-2016
Publisher
MICROBIOLOGICAL SOCIETY KOREA
Keywords
acyltransferase; autoinduction; Corynebacterium glutamicum; D-amino acid dehydrogenase; Pseudomonas aeruginosa
Citation
JOURNAL OF MICROBIOLOGY, v.54, no.6, pp.432 - 439
Indexed
SCIE
SCOPUS
KCI
Journal Title
JOURNAL OF MICROBIOLOGY
Volume
54
Number
6
Start Page
432
End Page
439
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/88484
DOI
10.1007/s12275-016-6046-3
ISSN
1225-8873
Abstract
Expression of a putative acyltransferase encoded by NCgl-0350 of Corynebacterium glutamicum is induced by cell-free culture fluids obtained from stationary-phase growth of both C. glutamicum and Pseudomonas aeruginosa, providing evidence for interspecies communication. Here, we further confirmed that such communication occurs by showing that acyltransferase expression is induced by culture fluid obtained from diverse Gram-negative and -positive bacterial strains, including Escherichia coli, Salmonella Typhimurium, Bacillus subtilis, Staphylococcus aureus, Mycobacterium sp. strain JC1, and Mycobacterium smegmatis. A homologous acyltransferase encoded by PA5238 of P. aeruginosa was also induced by fluids obtained from P. aeruginosa as well as other bacterial strains, as observed for NCgl0350 of C. glutamicum. Because C. glutamicum is difficult to study using molecular approaches, the homologous gene PA5238 of P. aeruginosa was used to identify PA5309 as an upstream regulator of expression. A homologous D-amino acid dehydrogenase encoded by NCgl2909 of C. glutamicum was cloned based on amino acid similarity to PA5309, and its role in the regulation of NCgl0350 expression was confirmed. Moreover, NCgl2909 played positive roles in growth of C. glutamicum. Thus, we identified a D-amino acid dehydrogenase as an upstream regulator of the autoinduction of a putative acyltransferase in C. glutamicum.
Files in This Item
There are no files associated with this item.
Appears in
Collections
Graduate School > Department of Biotechnology and Bioinformatics > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Ha, Un Hwan photo

Ha, Un Hwan
생명정보공학과
Read more

Altmetrics

Total Views & Downloads

BROWSE