Viscoelastic lithography for fabricating self-organizing soft micro-honeycomb structures with ultra-high aspect ratios
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jeong, Gi Seok | - |
dc.contributor.author | No, Da Yoon | - |
dc.contributor.author | Lee, JaeSeo | - |
dc.contributor.author | Yoon, Junghyo | - |
dc.contributor.author | Chung, Seok | - |
dc.contributor.author | Lee, Sang-Hoon | - |
dc.date.accessioned | 2021-09-04T00:14:24Z | - |
dc.date.available | 2021-09-04T00:14:24Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2016-05 | - |
dc.identifier.issn | 2041-1723 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/88811 | - |
dc.description.abstract | High-aspect ratio micro-and nano-structures have been used for the production of a variety of applications. In this paper, we describe a simple and cost-effective approach to fabricate an arrayed microarchitecture with an ultra-high aspect ratio using soft materials. The shapes and sizes of the honeycomb structure can be easily modulated by changing the dimensions and position of the base mould pattern and the pressure. The honeycomb structure is used to prepare a drug delivery patch and a microwell array to form cell spheroids without cell loss. The honeycomb structures prepared using natural ECM (collagen-Matrigel) materials are successfully fabricated. The hepatocytes and endothelial cells are seeded and co-cultured in the ECM-based micro-honeycomb to prepare a 3D liver model successfully mimicking an ultrastructure of liver and providing enhanced liver function. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | NATURE PUBLISHING GROUP | - |
dc.subject | SINUSOIDAL ENDOTHELIAL-CELLS | - |
dc.subject | BUBBLE PRESSURE METHOD | - |
dc.subject | EMBRYOID BODIES | - |
dc.subject | SURFACE-TENSION | - |
dc.subject | COCULTURE | - |
dc.subject | MICROFABRICATION | - |
dc.subject | NANOTUBES | - |
dc.subject | SCAFFOLDS | - |
dc.subject | HYDROGELS | - |
dc.subject | SYSTEM | - |
dc.title | Viscoelastic lithography for fabricating self-organizing soft micro-honeycomb structures with ultra-high aspect ratios | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Chung, Seok | - |
dc.contributor.affiliatedAuthor | Lee, Sang-Hoon | - |
dc.identifier.doi | 10.1038/ncomms11269 | - |
dc.identifier.scopusid | 2-s2.0-84971255177 | - |
dc.identifier.wosid | 000375490900001 | - |
dc.identifier.bibliographicCitation | NATURE COMMUNICATIONS, v.7 | - |
dc.relation.isPartOf | NATURE COMMUNICATIONS | - |
dc.citation.title | NATURE COMMUNICATIONS | - |
dc.citation.volume | 7 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.subject.keywordPlus | SINUSOIDAL ENDOTHELIAL-CELLS | - |
dc.subject.keywordPlus | BUBBLE PRESSURE METHOD | - |
dc.subject.keywordPlus | EMBRYOID BODIES | - |
dc.subject.keywordPlus | SURFACE-TENSION | - |
dc.subject.keywordPlus | COCULTURE | - |
dc.subject.keywordPlus | MICROFABRICATION | - |
dc.subject.keywordPlus | NANOTUBES | - |
dc.subject.keywordPlus | SCAFFOLDS | - |
dc.subject.keywordPlus | HYDROGELS | - |
dc.subject.keywordPlus | SYSTEM | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.