Tunicate-Inspired Gallic Acid/Metal Ion Complex for Instant and Efficient Treatment of Dentin Hypersensitivity
DC Field | Value | Language |
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dc.contributor.author | Prajatelistia, Ekavianty | - |
dc.contributor.author | Ju, Sung-Won | - |
dc.contributor.author | Sanandiya, Naresh D. | - |
dc.contributor.author | Jun, Sang Ho | - |
dc.contributor.author | Ahn, Jin-Soo | - |
dc.contributor.author | Hwang, Dong Soo | - |
dc.date.accessioned | 2021-09-04T00:26:49Z | - |
dc.date.available | 2021-09-04T00:26:49Z | - |
dc.date.created | 2021-06-17 | - |
dc.date.issued | 2016-04-20 | - |
dc.identifier.issn | 2192-2640 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/88904 | - |
dc.description.abstract | Dentin hypersensitivity is sharp and unpleasant pains caused by exposed dentinal tubules when enamel outside of the tooth wears away. The occlusion of dentinal tubules via in situ remineralization of hydroxyapatite is the best method to alleviate the symptoms caused by dentin hypersensitivity. Commercially available dental desensitizers are generally effective only on a specific area and are relatively toxic, and their performance usually depends on the skill of the clinician. Here, a facile and efficient dentin hypersensitivity treatment with remarkable aesthetic improvement inspired by the tunicate-self-healing process is reported. As pyrogallol groups in tunicate proteins conjugate with metal ions to heal the torn body armor of a tunicate, the ingenious mechanism by introducing gallic acid (GA) as a cheap, abundant, and edible alternative to the pyrogallol groups of the tunicate combined with a varied daily intake of metal ion sources is mimicked. In particular, the GA/Fe3+ complex exhibits the most promising results, to the instant approximate to 52% blockage in tubules within 4 min and approximate to 87% after 7 d of immersion in artificial saliva. Overall, the GA/metal ion complex-mediated coating is facile, instant, and effective, and is suggested as an aesthetic solution for treating dentin hypersensitivity. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | WILEY | - |
dc.subject | ENAMEL | - |
dc.subject | REMINERALIZATION | - |
dc.subject | GLUTARALDEHYDE | - |
dc.subject | CHEMISTRY | - |
dc.subject | TOXICITY | - |
dc.title | Tunicate-Inspired Gallic Acid/Metal Ion Complex for Instant and Efficient Treatment of Dentin Hypersensitivity | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Jun, Sang Ho | - |
dc.identifier.doi | 10.1002/adhm.201500878 | - |
dc.identifier.scopusid | 2-s2.0-84958231231 | - |
dc.identifier.wosid | 000374693700008 | - |
dc.identifier.bibliographicCitation | ADVANCED HEALTHCARE MATERIALS, v.5, no.8, pp.919 - 927 | - |
dc.relation.isPartOf | ADVANCED HEALTHCARE MATERIALS | - |
dc.citation.title | ADVANCED HEALTHCARE MATERIALS | - |
dc.citation.volume | 5 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 919 | - |
dc.citation.endPage | 927 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalWebOfScienceCategory | Engineering, Biomedical | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Biomaterials | - |
dc.subject.keywordPlus | TOXICITY | - |
dc.subject.keywordPlus | ENAMEL | - |
dc.subject.keywordPlus | REMINERALIZATION | - |
dc.subject.keywordPlus | GLUTARALDEHYDE | - |
dc.subject.keywordPlus | CHEMISTRY | - |
dc.subject.keywordAuthor | dentin hypersensitivity | - |
dc.subject.keywordAuthor | gallic acid | - |
dc.subject.keywordAuthor | hydroxyapatite | - |
dc.subject.keywordAuthor | TOPA | - |
dc.subject.keywordAuthor | tunicate | - |
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