Epidemiology and antimicrobial susceptibility profiles of pathogens causing urinary tract infections in the Asia-Pacific region: Results from the Study for Monitoring Antimicrobial Resistance Trends (SMART), 2010-2013
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jean, Shio-Shin | - |
dc.contributor.author | Coombs, Geoffrey | - |
dc.contributor.author | Ling, Thomas | - |
dc.contributor.author | Balaji, V. | - |
dc.contributor.author | Rodrigues, Camilla | - |
dc.contributor.author | Mikamo, Hiroshige | - |
dc.contributor.author | Kim, Min-Ja | - |
dc.contributor.author | Rajasekaram, Datin Ganeswrie | - |
dc.contributor.author | Mendoza, Myrna | - |
dc.contributor.author | Tan, Thean Yen | - |
dc.contributor.author | Kiratisin, Pattarachai | - |
dc.contributor.author | Ni, Yuxing | - |
dc.contributor.author | Weinman, Barry | - |
dc.contributor.author | Xu, Yingchun | - |
dc.contributor.author | Hsueh, Po-Ren | - |
dc.date.accessioned | 2021-09-04T00:52:00Z | - |
dc.date.available | 2021-09-04T00:52:00Z | - |
dc.date.created | 2021-06-17 | - |
dc.date.issued | 2016-04 | - |
dc.identifier.issn | 0924-8579 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/88973 | - |
dc.description.abstract | A total of 9599 isolates of Gram-negative bacteria (GNB) causing urinary tract infections (UTIs) were collected from 60 centres in 13 countries in the Asia-Pacific region from 2010-2013. These isolates comprised Enterobacteriaceae species (mainly Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Klebsiella oxytoca, Enterobacter cloacae and Morganella morganii) and non-fermentative GNB species (predominantly Pseudomonas aeruginosa and Acinetobacter baumannii). In vitro susceptibilities were determined by the agar dilution method and susceptibility profiles were determined using the minimum inhibitory concentration (MIC) interpretive breakpoints recommended by the Clinical and Laboratory Standards Institute in 2015. Production of extended-spectrum beta-lactamases (ESBLs) amongst E. coli, K. pneumoniae, P. mirabilis and K. oxytoca isolates was determined by the double-disk synergy test. China, Vietnam, India, Thailand and the Philippines had the highest rates of GNB species producing ESBLs and the highest rates of cephalosporin resistance. ESBL production and hospital-acquired infection (isolates obtained >= 48 h after admission) significantly compromised the susceptibility of isolates of E. coli and K. pneumoniae to ciprofloxacin, levofloxacin and most beta-lactams, with the exception of imipenem and ertapenem. However, > 87% of ESBL-producing E. coli strains were susceptible to amikacin and piperacillin/tazobactam, indicating that these antibiotics might be appropriate alternatives for treating UTIs due to ESBL-producing E. coli. Fluoroquinolones were shown to be inappropriate as empirical therapy for UTIs. Antibiotic resistance is a serious problem in the Asia-Pacific region. Therefore, continuous monitoring of evolutionary trends in the susceptibility profiles of GNB causing UTIs in Asia is crucial. (C) 2016 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE BV | - |
dc.subject | ESCHERICHIA-COLI | - |
dc.subject | PYELONEPHRITIS | - |
dc.subject | PREVALENCE | - |
dc.subject | TAIWAN | - |
dc.title | Epidemiology and antimicrobial susceptibility profiles of pathogens causing urinary tract infections in the Asia-Pacific region: Results from the Study for Monitoring Antimicrobial Resistance Trends (SMART), 2010-2013 | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Min-Ja | - |
dc.identifier.doi | 10.1016/j.ijantimicag.2016.01.008 | - |
dc.identifier.scopusid | 2-s2.0-84961218721 | - |
dc.identifier.wosid | 000373854500012 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, v.47, no.4, pp.328 - 334 | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | - |
dc.citation.title | INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | - |
dc.citation.volume | 47 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 328 | - |
dc.citation.endPage | 334 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Infectious Diseases | - |
dc.relation.journalResearchArea | Microbiology | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Infectious Diseases | - |
dc.relation.journalWebOfScienceCategory | Microbiology | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.subject.keywordPlus | ESCHERICHIA-COLI | - |
dc.subject.keywordPlus | PYELONEPHRITIS | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordPlus | TAIWAN | - |
dc.subject.keywordAuthor | Urinary tract infection | - |
dc.subject.keywordAuthor | Gram-negative bacteria | - |
dc.subject.keywordAuthor | Extended-spectrum beta-lactamase | - |
dc.subject.keywordAuthor | ESBL | - |
dc.subject.keywordAuthor | Susceptibility | - |
dc.subject.keywordAuthor | Hospital-acquired | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.