Efficacy of postoperative mitomycin-C eye drops on the clinical outcome in endoscopic dacryocystorhinostomy
DC Field | Value | Language |
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dc.contributor.author | Do, Jae Rock | - |
dc.contributor.author | Lee, Hwa | - |
dc.contributor.author | Baek, Sehyun | - |
dc.contributor.author | Lee, Tae Soo | - |
dc.contributor.author | Chang, Minwook | - |
dc.date.accessioned | 2021-09-04T01:04:22Z | - |
dc.date.available | 2021-09-04T01:04:22Z | - |
dc.date.created | 2021-06-17 | - |
dc.date.issued | 2016-04 | - |
dc.identifier.issn | 0721-832X | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/89063 | - |
dc.description.abstract | To evaluate the effect of postoperative topical mitomycin-C (MMC) eye drops in endoscopic (dacryocystorhinostomy) DCR and compare them with intraoperative MMC soaking. Retrospective, nonrandomized, interventional case series. One hundred and sixty cases of endoscopic DCR with a single surgeon for primary nasolacrimal duct obstruction (NLDO) were included. Cases were divided into three groups. Group 1 was treated with intraoperative application of 0.02 % MMC for 5 min. Group 2 was treated with 0.02 % MMC eye drops for 5 days after surgery, without intraoperative application of MMC. Group 3 was the control group of cases without the use of MMC. Each group was evaluated for surgical success, presence of complications including granuloma, synechiae, and tube-induced inflammation, and the adverse effect of the MMC at least 6 months after the surgery. The success rate showed no significant difference among the three groups (P = .122, chi-square analysis). In the analysis between the two groups, although the success rate of Group 2 appeared not to be statistically different compared with that of Group 1 (P = .419, chi-square analysis), Group 2 had a statistically higher success rate for surgery than Group 3 (P = .041, chi-square analysis). The presence of granuloma was significantly lower in Group 1 than in the other two groups (P = .022, chi-square analysis). Synechiae and silicone tube-induced inflammation were not significantly different (P = .308, P = .881, chi-square analysis). There were no adverse effects associated with intraoperative or postoperative MMC application. Use of postoperative topical 0.02 % MMC is a safe and effective adjunctive modality to increase the success rate of endoscopic DCR. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | SPRINGER | - |
dc.subject | NASAL-MUCOSA FIBROBLASTS | - |
dc.subject | INTRAEPITHELIAL NEOPLASIA | - |
dc.subject | SURGICAL OUTCOMES | - |
dc.subject | PTERYGIUM SURGERY | - |
dc.subject | COMPLICATIONS | - |
dc.title | Efficacy of postoperative mitomycin-C eye drops on the clinical outcome in endoscopic dacryocystorhinostomy | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Hwa | - |
dc.contributor.affiliatedAuthor | Baek, Sehyun | - |
dc.identifier.doi | 10.1007/s00417-015-3229-2 | - |
dc.identifier.scopusid | 2-s2.0-84961215489 | - |
dc.identifier.wosid | 000372608100022 | - |
dc.identifier.bibliographicCitation | GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, v.254, no.4, pp.785 - 790 | - |
dc.relation.isPartOf | GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY | - |
dc.citation.title | GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY | - |
dc.citation.volume | 254 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 785 | - |
dc.citation.endPage | 790 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Ophthalmology | - |
dc.relation.journalWebOfScienceCategory | Ophthalmology | - |
dc.subject.keywordPlus | NASAL-MUCOSA FIBROBLASTS | - |
dc.subject.keywordPlus | INTRAEPITHELIAL NEOPLASIA | - |
dc.subject.keywordPlus | SURGICAL OUTCOMES | - |
dc.subject.keywordPlus | PTERYGIUM SURGERY | - |
dc.subject.keywordPlus | COMPLICATIONS | - |
dc.subject.keywordAuthor | Dacryocystorhinostomy | - |
dc.subject.keywordAuthor | Endoscopy | - |
dc.subject.keywordAuthor | Mitomycin | - |
dc.subject.keywordAuthor | Nasolacrimal duct | - |
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