Simple and Biocompatible Ion Beam Micropatterning of a Cell-Repellent Polymer on Cell-Adhesive Surfaces to Manipulate Cell Adhesion
DC Field | Value | Language |
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dc.contributor.author | Hwang, In-Tae | - |
dc.contributor.author | Jung, Chan-Hee | - |
dc.contributor.author | Jung, Chang-Hee | - |
dc.contributor.author | Choi, Jae-Hak | - |
dc.contributor.author | Shin, Kwanwoo | - |
dc.contributor.author | Yoo, Young-Do | - |
dc.date.accessioned | 2021-09-04T03:21:50Z | - |
dc.date.available | 2021-09-04T03:21:50Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2016-02 | - |
dc.identifier.issn | 1550-7033 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/89608 | - |
dc.description.abstract | In this paper, the simple and biocompatible micropatterning of cell-repellent poly(N-isopropylacrylamide) (PNIPAAm) on a cell-adhesive substrate by ion beam micropatterning to control cell adhesion is described. Cell-repellent PNIPAAm films spin-coated on cell-adhesive tissue culture polystyrene (TCPS) substrates were selectively irradiated by energetic proton ions at various fluences through a pattern mask, and subsequently developed to create the micropatterns of PNIPAAm. Well-defined negative-type PNIPAAm micropatterns were successfully created on the TCPS substrates at fluences higher than 5 x 10(14) ions/cm(2), and their chemical properties were dependent on the fluence. Moreover, based on the results of the protein adsorption and in-vitro cell culture tests, 200 mu m well-defined micropatterns of mammalian cells were clearly formed on the PNIPAAm-micropatterned TCPS substrates though the preferential adsorption and growth of cells on the TCPS regions due to the strong cell-repellency of PNIPAAm. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | AMER SCIENTIFIC PUBLISHERS | - |
dc.subject | FABRICATION | - |
dc.subject | CULTURE | - |
dc.title | Simple and Biocompatible Ion Beam Micropatterning of a Cell-Repellent Polymer on Cell-Adhesive Surfaces to Manipulate Cell Adhesion | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Yoo, Young-Do | - |
dc.identifier.doi | 10.1166/jbn.2016.2184 | - |
dc.identifier.scopusid | 2-s2.0-84959367794 | - |
dc.identifier.wosid | 000371449400014 | - |
dc.identifier.bibliographicCitation | JOURNAL OF BIOMEDICAL NANOTECHNOLOGY, v.12, no.2, pp.387 - 393 | - |
dc.relation.isPartOf | JOURNAL OF BIOMEDICAL NANOTECHNOLOGY | - |
dc.citation.title | JOURNAL OF BIOMEDICAL NANOTECHNOLOGY | - |
dc.citation.volume | 12 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 387 | - |
dc.citation.endPage | 393 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Biomaterials | - |
dc.subject.keywordPlus | FABRICATION | - |
dc.subject.keywordPlus | CULTURE | - |
dc.subject.keywordAuthor | PNIPAAm | - |
dc.subject.keywordAuthor | Cell Micropatterns | - |
dc.subject.keywordAuthor | Ion Irradiation | - |
dc.subject.keywordAuthor | Tissue Culture Polystyrene | - |
dc.subject.keywordAuthor | Protein Adsorption | - |
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