The effects of Chamaecyparis obtusa essential oil on pain-related behavior and expression of pro-inflammatory cytokines in carrageenan-induced arthritis in rats
DC Field | Value | Language |
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dc.contributor.author | Suh, Hye Rim | - |
dc.contributor.author | Chung, Hyun Joo | - |
dc.contributor.author | Park, Eui Ho | - |
dc.contributor.author | Moon, Sun Wook | - |
dc.contributor.author | Park, Su Jin | - |
dc.contributor.author | Park, Chan Woo | - |
dc.contributor.author | Kim, Yang In | - |
dc.contributor.author | Han, Hee Chul | - |
dc.date.accessioned | 2021-09-04T04:14:30Z | - |
dc.date.available | 2021-09-04T04:14:30Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2016-01-02 | - |
dc.identifier.issn | 0916-8451 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/89852 | - |
dc.description.abstract | Chamaecyparis obtusa essential oil (COE) has been widely used to treat allergic diseases and was suggested to exert anti-inflammatory, antioxidant, and antimicrobial effects. This study evaluated the effects of COE on pain-related behavior and pro-inflammatory cytokines in rats with carrageenan (CGN)-induced arthritis. Reduced dynamic weight load on inflamed joint in voluntarily walking rats was used as the behavior test for arthritic pain; 10% COE-treated group was significantly attenuated pain (6-8h post-CGN injection) compared to VEH (mineral oil)-treated group. In addition, the protein levels of interleukin (IL)-1, tumor necrosis factor-, IL-6 (6-8h), and cyclooxygenase (COX)-2 (8h) within the synovial membrane, as well as IL-1, COX-2 (6-8h), and IL-6 (5-7h) within the meniscus, of 10% COE-treated group were significantly reduced. The current results implicate that COE has anti-inflammatory and anti-nociceptive effects on arthritis in rats. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | TAYLOR & FRANCIS LTD | - |
dc.subject | NECROSIS-FACTOR-ALPHA | - |
dc.subject | PROSTAGLANDIN E-2 | - |
dc.subject | CORDIA-VERBENACEA | - |
dc.subject | ACTIVE COMPOUNDS | - |
dc.subject | CYCLOOXYGENASE-2 | - |
dc.subject | OSTEOARTHRITIS | - |
dc.subject | EXPLANTS | - |
dc.subject | LPS | - |
dc.title | The effects of Chamaecyparis obtusa essential oil on pain-related behavior and expression of pro-inflammatory cytokines in carrageenan-induced arthritis in rats | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Yang In | - |
dc.contributor.affiliatedAuthor | Han, Hee Chul | - |
dc.identifier.doi | 10.1080/09168451.2015.1075864 | - |
dc.identifier.scopusid | 2-s2.0-84958965122 | - |
dc.identifier.wosid | 000365627500028 | - |
dc.identifier.bibliographicCitation | BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, v.80, no.1, pp.203 - 209 | - |
dc.relation.isPartOf | BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | - |
dc.citation.title | BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | - |
dc.citation.volume | 80 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 203 | - |
dc.citation.endPage | 209 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Biotechnology & Applied Microbiology | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Food Science & Technology | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Applied | - |
dc.relation.journalWebOfScienceCategory | Food Science & Technology | - |
dc.subject.keywordPlus | NECROSIS-FACTOR-ALPHA | - |
dc.subject.keywordPlus | PROSTAGLANDIN E-2 | - |
dc.subject.keywordPlus | CORDIA-VERBENACEA | - |
dc.subject.keywordPlus | ACTIVE COMPOUNDS | - |
dc.subject.keywordPlus | CYCLOOXYGENASE-2 | - |
dc.subject.keywordPlus | OSTEOARTHRITIS | - |
dc.subject.keywordPlus | EXPLANTS | - |
dc.subject.keywordPlus | LPS | - |
dc.subject.keywordAuthor | Chamaecyparis obtusa essential oil | - |
dc.subject.keywordAuthor | carrageenan-induced arthritis | - |
dc.subject.keywordAuthor | pro-inflammatory cytokines | - |
dc.subject.keywordAuthor | dynamic weight load | - |
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