Separation and sorting of cells in microsystems using physical principles
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Gi-Hun | - |
dc.contributor.author | Kim, Sung-Hwan | - |
dc.contributor.author | Ahn, Kihoon | - |
dc.contributor.author | Lee, Sang-Hoon | - |
dc.contributor.author | Park, Joong Yull | - |
dc.date.accessioned | 2021-09-04T04:34:26Z | - |
dc.date.available | 2021-09-04T04:34:26Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2016-01 | - |
dc.identifier.issn | 0960-1317 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/89977 | - |
dc.description.abstract | In the last decade, microfabrication techniques have been combined with microfluidics and applied to cell biology. Utilizing such new techniques, various cell studies have been performed for the research of stem cells, immune cells, cancer, neurons, etc. Among the various biological applications of microtechnology-based platforms, cell separation technology has been highly regarded in biological and clinical fields for sorting different types of cells, finding circulating tumor cells (CTCs), and blood cell separation, amongst other things. Many cell separation methods have been created using various physical principles. Representatively, these include hydrodynamic, acoustic, dielectrophoretic, magnetic, optical, and filtering methods. In this review, each of these methods will be introduced, and their physical principles and sample applications described. Each physical principle has its own advantages and disadvantages. The engineers who design the systems and the biologists who use them should understand the pros and cons of each method or principle, to broaden the use of microsystems for cell separation. Continuous development of microsystems for cell separation will lead to new opportunities for diagnosing CTCs and cancer metastasis, as well as other elements in the bloodstream. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | IOP PUBLISHING LTD | - |
dc.subject | CIRCULATING TUMOR-CELLS | - |
dc.subject | CONTINUOUS PARTICLE SEPARATION | - |
dc.subject | ACOUSTIC-WAVE | - |
dc.subject | WHOLE-BLOOD | - |
dc.subject | FLOW | - |
dc.subject | MANIPULATION | - |
dc.subject | MICROFLUIDICS | - |
dc.subject | DEVICE | - |
dc.subject | DIELECTROPHORESIS | - |
dc.subject | MICROFILTRATION | - |
dc.title | Separation and sorting of cells in microsystems using physical principles | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Sang-Hoon | - |
dc.identifier.doi | 10.1088/0960-1317/26/1/013003 | - |
dc.identifier.scopusid | 2-s2.0-84951077182 | - |
dc.identifier.wosid | 000366868700005 | - |
dc.identifier.bibliographicCitation | JOURNAL OF MICROMECHANICS AND MICROENGINEERING, v.26, no.1 | - |
dc.relation.isPartOf | JOURNAL OF MICROMECHANICS AND MICROENGINEERING | - |
dc.citation.title | JOURNAL OF MICROMECHANICS AND MICROENGINEERING | - |
dc.citation.volume | 26 | - |
dc.citation.number | 1 | - |
dc.type.rims | ART | - |
dc.type.docType | Review | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Instruments & Instrumentation | - |
dc.relation.journalResearchArea | Physics | - |
dc.relation.journalWebOfScienceCategory | Engineering, Electrical & Electronic | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Instruments & Instrumentation | - |
dc.relation.journalWebOfScienceCategory | Physics, Applied | - |
dc.subject.keywordPlus | CIRCULATING TUMOR-CELLS | - |
dc.subject.keywordPlus | CONTINUOUS PARTICLE SEPARATION | - |
dc.subject.keywordPlus | ACOUSTIC-WAVE | - |
dc.subject.keywordPlus | WHOLE-BLOOD | - |
dc.subject.keywordPlus | FLOW | - |
dc.subject.keywordPlus | MANIPULATION | - |
dc.subject.keywordPlus | MICROFLUIDICS | - |
dc.subject.keywordPlus | DEVICE | - |
dc.subject.keywordPlus | DIELECTROPHORESIS | - |
dc.subject.keywordPlus | MICROFILTRATION | - |
dc.subject.keywordAuthor | cell separation | - |
dc.subject.keywordAuthor | acoustic | - |
dc.subject.keywordAuthor | dielectrophoretic | - |
dc.subject.keywordAuthor | hydrodynamic | - |
dc.subject.keywordAuthor | magnetic | - |
dc.subject.keywordAuthor | optical | - |
dc.subject.keywordAuthor | filtering | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.