Adherence to Guidelines for Antithrombotic Therapy in Patients with Atrial Fibrillation According to CHADS2 Score before and after Stroke: A Multicenter Observational Study from Korea
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Wook-Joo | - |
dc.contributor.author | Park, Jong-Moo | - |
dc.contributor.author | Kang, Kyusik | - |
dc.contributor.author | Cho, Yong-Jin | - |
dc.contributor.author | Hong, Keun-Sik | - |
dc.contributor.author | Lee, Soo Joo | - |
dc.contributor.author | Ko, Youngchai | - |
dc.contributor.author | Lee, Kyung Bok | - |
dc.contributor.author | Park, Tai Hwan | - |
dc.contributor.author | Lee, Jun | - |
dc.contributor.author | Cha, Jae-Kwan | - |
dc.contributor.author | Kim, Dae-Hyun | - |
dc.contributor.author | Yu, Kyung-Ho | - |
dc.contributor.author | Lee, Byung-Chul | - |
dc.contributor.author | Oh, Mi-Sun | - |
dc.contributor.author | Lee, Juneyoung | - |
dc.contributor.author | Lee, JiSung | - |
dc.contributor.author | Jang, Myung Suk | - |
dc.contributor.author | Han, Moon-Ku | - |
dc.contributor.author | Bae, Hee-Joon | - |
dc.date.accessioned | 2021-09-04T04:44:58Z | - |
dc.date.available | 2021-09-04T04:44:58Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2016-01 | - |
dc.identifier.issn | 1738-6586 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/90056 | - |
dc.description.abstract | Background and Purpose A substantial proportion of patients with atrial fibrillation (AF) are not treated optimally; however, the inappropriateness of drug therapy has never been evaluated before or after a stroke event. We investigated the adherence to guidelines for therapy in AF patients hospitalized with acute ischemic stroke (AIS) before stroke onset and at discharge, with the aim of identifying the factors associated with inappropriate therapy. Methods AIS patients with AF hospitalized within 7 days of onset were identified from a prospective nine-center stroke registry database. Two cohorts were defined: patients diagnosed with AF prior to the stroke event (admission cohort) and patients diagnosed with AF at discharge from hospital (discharge cohort). Any of the following conditions were regarded as nonadherence to guidelines in this study: use of anticoagulant or nonuse of antithrombotics with CHADS2 score=0, nonuse of antithrombotics with CHADS2 score=1, or nonuse of anticoagulant with CHADS2 score >= 2. Results Overall, 406 patients were enrolled in the admission cohort and 518 in the discharge cohort. The rates of nonadherence before a stroke event and at discharge were 77.8% and 33.3%, respectively. These rates varied widely for both cohorts, with interhospital differences being statistically significant. Multivariable analysis revealed that old age, stroke history, and congestive heart failure were associated with nonadherence before stroke. At discharge, males, coronary heart disease, inappropriate antithrombotic use before stroke, and functional disability at discharge were associated with nonadherence. Conclusions This study shows that antithrombotic use in AIS patients with AF might be not optimal before and after stroke in Korea. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KOREAN NEUROLOGICAL ASSOC | - |
dc.subject | EURO HEART SURVEY | - |
dc.subject | ORAL ANTICOAGULATION | - |
dc.subject | RISK STRATIFICATION | - |
dc.subject | PREDICTING STROKE | - |
dc.subject | ELDERLY-PATIENTS | - |
dc.subject | WARFARIN USE | - |
dc.subject | PREVENTION | - |
dc.subject | MANAGEMENT | - |
dc.subject | ASPIRIN | - |
dc.title | Adherence to Guidelines for Antithrombotic Therapy in Patients with Atrial Fibrillation According to CHADS2 Score before and after Stroke: A Multicenter Observational Study from Korea | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Juneyoung | - |
dc.identifier.doi | 10.3988/jcn.2016.12.1.34 | - |
dc.identifier.scopusid | 2-s2.0-84954319094 | - |
dc.identifier.wosid | 000367278300004 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CLINICAL NEUROLOGY, v.12, no.1, pp.34 - 41 | - |
dc.relation.isPartOf | JOURNAL OF CLINICAL NEUROLOGY | - |
dc.citation.title | JOURNAL OF CLINICAL NEUROLOGY | - |
dc.citation.volume | 12 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 34 | - |
dc.citation.endPage | 41 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002061671 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.subject.keywordPlus | EURO HEART SURVEY | - |
dc.subject.keywordPlus | ORAL ANTICOAGULATION | - |
dc.subject.keywordPlus | RISK STRATIFICATION | - |
dc.subject.keywordPlus | PREDICTING STROKE | - |
dc.subject.keywordPlus | ELDERLY-PATIENTS | - |
dc.subject.keywordPlus | WARFARIN USE | - |
dc.subject.keywordPlus | PREVENTION | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | ASPIRIN | - |
dc.subject.keywordAuthor | atrial fibrillation | - |
dc.subject.keywordAuthor | drug utilization review | - |
dc.subject.keywordAuthor | cerebral infarction | - |
dc.subject.keywordAuthor | guideline adherence | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
145 Anam-ro, Seongbuk-gu, Seoul, 02841, Korea+82-2-3290-2963
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.