Diterpenoids from the Roots of Euphorbia fischeriana with Inhibitory Effects on Nitric Oxide Production
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Jin Woo | - |
dc.contributor.author | Lee, Chul | - |
dc.contributor.author | Jin, Qinghao | - |
dc.contributor.author | Jang, Hari | - |
dc.contributor.author | Lee, Dongho | - |
dc.contributor.author | Lee, Ha-Jin | - |
dc.contributor.author | Shin, Jong Won | - |
dc.contributor.author | Han, Sang Bae | - |
dc.contributor.author | Hong, Jin Tae | - |
dc.contributor.author | Kim, Youngsoo | - |
dc.contributor.author | Lee, Mi Kyeong | - |
dc.contributor.author | Hwang, Bang Yeon | - |
dc.date.accessioned | 2021-09-04T04:45:21Z | - |
dc.date.available | 2021-09-04T04:45:21Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2016-01 | - |
dc.identifier.issn | 0163-3864 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/90058 | - |
dc.description.abstract | Bioactivity-guided isolation of a methanolic extract of Euphorbia fischeriana led to the isolation of four new abietane-type diterpenoids, fischeriolides A-D (1-4), together with 11 known diterpenoids. Their structures were elucidated based on the interpretation of 1D and 2D NMR spectroscopic and HRESIMS data. The absolute configuration of compound 3 was determined by single-crystal X-ray diffraction analysis and electronic circular dichroism methods. Compounds 5-9 exhibited inhibitory effects on LPS-induced nitric oxide production in RAW 264.7 macrophages with IC50 values in the range 4.9-12.6 mu M. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.subject | NO PRODUCTION | - |
dc.subject | EBRACTEOLATA | - |
dc.title | Diterpenoids from the Roots of Euphorbia fischeriana with Inhibitory Effects on Nitric Oxide Production | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Dongho | - |
dc.identifier.doi | 10.1021/acs.jnatprod.5b00789 | - |
dc.identifier.scopusid | 2-s2.0-84956709676 | - |
dc.identifier.wosid | 000368755000016 | - |
dc.identifier.bibliographicCitation | JOURNAL OF NATURAL PRODUCTS, v.79, no.1, pp.126 - 131 | - |
dc.relation.isPartOf | JOURNAL OF NATURAL PRODUCTS | - |
dc.citation.title | JOURNAL OF NATURAL PRODUCTS | - |
dc.citation.volume | 79 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 126 | - |
dc.citation.endPage | 131 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Plant Sciences | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Plant Sciences | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.subject.keywordPlus | NO PRODUCTION | - |
dc.subject.keywordPlus | EBRACTEOLATA | - |
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