ScholarWorks@Korea University

Detailed Information

Cited 0 time in webofscience Cited 0 time in scopus
Metadata Downloads

Sesquiterpenoids from Tussilago farfara inhibit LPS-induced nitric oxide production in macrophage RAW 264.7 cells

Full metadata record
DC Field Value Language
dc.contributor.authorJang, Hari-
dc.contributor.authorLee, Jin Woo-
dc.contributor.authorLee, Chul-
dc.contributor.authorJin, Qinghao-
dc.contributor.authorChoi, Jeong Yeon-
dc.contributor.authorLee, Dongho-
dc.contributor.authorHan, Sang Bae-
dc.contributor.authorKim, Youngsoo-
dc.contributor.authorHong, Jin Tae-
dc.contributor.authorLee, Mi Kyeong-
dc.contributor.authorHwang, Bang Yeon-
dc.date.accessioned2021-09-04T04:48:05Z-
dc.date.available2021-09-04T04:48:05Z-
dc.date.created2021-06-18-
dc.date.issued2016-01-
dc.identifier.issn0253-6269-
dc.identifier.urihttps://scholar.korea.ac.kr/handle/2021.sw.korea/90078-
dc.description.abstractA new oplopane-type sesquiterpenoid tussilagofarin (1) and a new chromone tussilagofarol (2), along with 18 known compounds 3-20, were isolated from the flower buds of Tussilago farfara. The structures of the new compounds were elucidated on the basis of 1D and 2D NMR and HRESIMS data. Of the isolated compounds, oplopane- and bisabolane-type sesquterpenoids 1, 8-12, 15, and 16 were found to inhibit nitric oxide production in LPS-induced RAW 264.7 cells with IC50 values of 3.5-28.5 mu M.-
dc.languageEnglish-
dc.language.isoen-
dc.publisherPHARMACEUTICAL SOC KOREA-
dc.subjectOCCURRING TERPENE DERIVATIVES-
dc.subjectFLOWER BUDS-
dc.subjectCONSTITUENTS-
dc.subjectEXTRACTION-
dc.titleSesquiterpenoids from Tussilago farfara inhibit LPS-induced nitric oxide production in macrophage RAW 264.7 cells-
dc.typeArticle-
dc.contributor.affiliatedAuthorLee, Dongho-
dc.identifier.doi10.1007/s12272-015-0667-7-
dc.identifier.scopusid2-s2.0-84954230219-
dc.identifier.wosid000368200100014-
dc.identifier.bibliographicCitationARCHIVES OF PHARMACAL RESEARCH, v.39, no.1, pp.127 - 132-
dc.relation.isPartOfARCHIVES OF PHARMACAL RESEARCH-
dc.citation.titleARCHIVES OF PHARMACAL RESEARCH-
dc.citation.volume39-
dc.citation.number1-
dc.citation.startPage127-
dc.citation.endPage132-
dc.type.rimsART-
dc.type.docTypeArticle-
dc.identifier.kciidART002075465-
dc.description.journalClass1-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.description.journalRegisteredClasskci-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryPharmacology & Pharmacy-
dc.subject.keywordPlusOCCURRING TERPENE DERIVATIVES-
dc.subject.keywordPlusFLOWER BUDS-
dc.subject.keywordPlusCONSTITUENTS-
dc.subject.keywordPlusEXTRACTION-
dc.subject.keywordAuthorTussilago farfara-
dc.subject.keywordAuthorAsteraceae-
dc.subject.keywordAuthorOplopane-type-
dc.subject.keywordAuthorsesquiterpenoid-
dc.subject.keywordAuthorNitric oxide production inhibitor-
Files in This Item
There are no files associated with this item.
Appears in
Collections
Graduate School > Department of Plant Biotechnology > 1. Journal Articles
Show simple item record

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Lee, Dong ho photo

Lee, Dong ho
식물생명공학과
Read more

Altmetrics

Total Views & Downloads

STATISTICS
Total View :8,725,835
Today View :7,580

RSS_1.0 RSS_2.0 ATOM_1.0

CONTACT US

(02841) 서울특별시 성북구 안암로 14502-3290-1114

COPYRIGHT © 2021 Korea University. All Rights Reserved.

Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.

BROWSE

English