구제요법으로 시행한 소라페닙 치료에 극적인 반응을 보인 폐전이를동반한 진행성 간세포암종 1예Regression of Advanced Hepatocellular Carcinoma with Lung Metastasis in Response to Sorafenib
- Other Titles
- Regression of Advanced Hepatocellular Carcinoma with Lung Metastasis in Response to Sorafenib
- Authors
- 김대하; 민지호; 이동원; 안계련; 김지혜; 서상준; 정영걸; 임형준
- Issue Date
- 2016
- Publisher
- 대한간암학회
- Keywords
- Carcinoma; Hepatocellular; Drug therapy; Sorafenib; Treatment outcome
- Citation
- Journal of Liver Cancer, v.16, no.1, pp.57 - 62
- Indexed
- KCI
OTHER
- Journal Title
- Journal of Liver Cancer
- Volume
- 16
- Number
- 1
- Start Page
- 57
- End Page
- 62
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/91016
- ISSN
- 2288-8128
- Abstract
- Sorafenib is a multi-targeted tyrosine kinase inhibitor that inhibits Raf kinase and the vascular endothelial growth factor receptor intracellular kinase pathway and is the first agent to demonstrate a statistically significant improvement in overall survival for patients with advanced hepatocellular carcinoma (HCC). However, there were few cases of partial or complete response reported in the previous studies. We herein report a case of dramatic partial response in a patient who had advanced HCC with multiple lung metastasis and portal vein thrombosis treated with sorafenib.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
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